老年非酒精性脂肪肝患者的危险因素分析
Analysis of Risk Factors of Non-Alcoholic Fatty Liver Disease in Elderly Patients
摘要: 目的：探讨影响老年非酒精性脂肪肝病(NAFLD)的危险因素，并分析影响因素与NAFLD的相关性。方法：选取2022年12月至2023年6月于青岛大学附属医院保健科就诊的274例患者，分为NAFLD组和非NAFLD组。收集两组的一般临床资料、实验室检查指标等，采用Logistic回归分析探究老年NAFLD患者的危险因素。结果：NAFLD组的体重、BMI、腰围、腰围/身高比、小腿围、高血压的比例、低密度脂蛋白、TryG、TryG-waist height、甘油三酯、空腹血糖均高于非NAFLD组(P < 0.05)。NAFLD组的高密度脂蛋白水平显著低于非NAFLD组(P < 0.05)。Logistic分析结果显示，小腿围、甘油三酯、腰围及罹患高血压是NAFLD的危险因素(P < 0.05)。结论：小腿围、腰围、甘油三酯、高血压与NAFLD呈正相关，该指标在病情评估中展现出良好的预测价值，具备操作简便、成本低廉、重复性高等优势，适用于临床并值得推广。
Abstract: Objective: To explore the risk factors of non-alcoholic fatty liver disease (NAFLD) in the elderly and analyze the correlation between the risk factors and NAFLD. Methods: 274 patients who visited the Health Care Department of The Affiliated Hospital of Qingdao University from December 2022 to June 2023 were selected and divided into NAFLD group and non-NAFLD group. General clinical data and laboratory test indicators from both groups were collected, and Logistic regression analysis was used to investigate the risk factors for elderly NAFLD patients. Result: The weight, BMI, waist circumference, waist-to-height ratio, calf circumference, proportion of hypertension, low-density lipoprotein, triglycerides (TryG), TryG-waist height ratio, triglycerides, and fasting blood glucose of the NAFLD group were all higher than those of the non-NAFLD group (P < 0.05). The high-density lipoprotein (HDL) levels in the NAFLD group were significantly lower than those in the non-NAFLD group (P < 0.05). Logistic analysis results showed that calf circumference, triglycerides, waist circumference, and hypertension were risk factors for NAFLD (P < 0.05). Conclusion: Calf circumference, waist circumference, triglycerides, and hypertension are positively correlated with NAFLD. These indicators show good predictive value in disease assessment, featuring simplicity of operation, low cost, and high repeatability. They are suitable for clinical use and worthy of promotion.
文章引用：徐梦茹, 胡松, 刘佳, 毛拥军. 老年非酒精性脂肪肝患者的危险因素分析[J]. 临床医学进展, 2025, 15(3): 1639-1645. https://doi.org/10.12677/acm.2025.153786

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