肌松闭环输注系统在全麻手术中的应用

Application of Muscle Relaxation Closed-Loop Infusion System in General Anesthesia Surgery

摘要: 肌松药的使用已经成为现代麻醉中的重要组成部分，但是手术麻醉中肌松药的使用不当容易引起一系列的不良反应。传统的给药方式有单次给药和持续输注两种方式，单次给药容易造成肌松不足或者过量，难以维持稳定的血药浓度，持续输注可以维持稳定的血药浓度，但缺少个体化，闭环肌松注射系统是一种通过肌松数据监测进行自动反馈闭环给药的注射系统；这种方法既避免了肌松不足或者过量，维持了稳定的血药浓度，又实现了个体化和合理化。本文通过查阅大量文献，就闭环肌松输注系统在手术中的应用进行总结，目的是为临床手术患者围术期肌松的精细化管理提供一定的理论依据。

Abstract: The use of muscle relaxants has become an essential part of modern anesthesia; however, improper use of muscle relaxants in surgical anesthesia can easily lead to a series of adverse reactions. Traditional administration methods include single-dose and continuous infusion. Single-dose administration can result in insufficient or excessive relaxation, making it difficult to maintain stable blood drug concentrations. Continuous infusion can maintain stable blood drug concentrations but still lacks personalization. Closed-loop muscle relaxation injection system is a kind of injection system that uses muscle relaxation data monitoring for automatic feedback and closed-loop dosing. This method not only avoids insufficient or excessive relaxation and maintains stable blood drug concentration, but also achieves personalization and rationality. This article summarizes the application of closed-loop muscle relaxation infusion systems in surgery by reviewing extensive literature, aiming to provide theoretical support for the precise management of perioperative muscle relaxation in clinical surgical patients.