镁涂层修饰的多孔钛合金骨科植入物研究进展
Advancements in Research on Magnesium-Coated Porous Titanium Alloy Orthopedic Implants
DOI: 10.12677/acm.2025.153798, PDF,   
作者: 郑增辉：西安医学院研究生院，陕西 西安
关键词: 镁涂层；骨整合；多孔钛合金；生物活性；Magnesium Coating； Osseointegration； Porous Titanium Alloy； Bioactivity
摘要: 多孔钛合金作为一种生物惰性材料，表面缺乏有效的生物活性成分，骨整合性不足。表面改性是提升其骨整合性的有效策略。镁作为人体必需微量元素，其离子可显著促进成骨作用，但纯镁耐腐蚀性差与力学强度低，这限制了其应用。将镁以涂层形式修饰于多孔钛合金表面，可结合两者的优势，但目前尚未见相关临床应用的系统性报道。本文综述了镁涂层修饰的多孔钛合金骨科植入物研究进展，重点探讨其在骨整合促进、促血管生成及感染风险降低等方面的潜力，并分析其安全性及制备工艺，以期为临床转化提供理论支持。
Abstract: Porous titanium alloys, as bioinert materials, lack effective bioactive components on their surfaces, resulting in insufficient osseointegration. Surface modification is an effective strategy to enhance their osseointegration. Magnesium, an essential trace element in the human body, can significantly promote osteogenesis through its ions. However, pure magnesium suffers from poor corrosion resistance and low mechanical strength, limiting its application. Modifying the surface of porous titanium alloys with magnesium in the form of a coating can combine the advantages of both materials, yet systematic reports on related clinical applications are currently lacking. This article reviews the research progress on magnesium-coated porous titanium alloy orthopedic implants, focusing on their potential to enhance osseointegration, promote angiogenesis, and reduce infection risk. It also analyzes their safety and preparation processes, aiming to provide theoretical support for clinical translation.
文章引用：郑增辉. 镁涂层修饰的多孔钛合金骨科植入物研究进展[J]. 临床医学进展, 2025, 15(3): 1731-1737. https://doi.org/10.12677/acm.2025.153798

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