医用缝合线的研究进展
Research Progress of Medical Sutures
DOI: 10.12677/acm.2025.153804, PDF,   
作者: 潘 江：赣南医科大学第一临床医学院，江西 赣州；谢林海*：赣南医科大学第一附属医院整形外科，江西 赣州
关键词: 医用缝合线；可吸收缝合线；不可吸收缝合线；Medical Sutures； Absorbable Suture； Non-Absorbable Suture
摘要: 随着工业科技的发展与伤口愈合理念、缝合技术的革新，缝合材料也在不断地更新，其材质、形态和功能表现出多样化，越来越迎合医患对缝合目的和效果的要求。本文就医用缝合线的发展及不同缝合线的特点作一综述，以期为外科医生选择合适缝合材料、尽可能地促进伤口愈合和减小瘢痕提供参考。
Abstract: With the development of industrial technology and the innovation of wound healing concepts and suture techniques, medical sutures are constantly being updated. Their materials, forms, and functions have become diverse, increasingly meeting the requirements of doctors and patients regarding the purpose and effect of sutures. This article reviews the development of medical sutures and their different characteristics, aiming to provide references for surgeons to select appropriate suture materials, promote wound healing to the greatest extent possible, and minimize scarring.
文章引用：潘江, 谢林海. 医用缝合线的研究进展[J]. 临床医学进展, 2025, 15(3): 1774-1779. https://doi.org/10.12677/acm.2025.153804

参考文献

[1] Gupta, V. (2024) Potential of Natural Plant-Based Materials in the Development of Biocompatible Drug-Eluting Surgical Sutures: A Review. Biomedical Materials & Device. [Google Scholar] [CrossRef] 
[2] Syukri, D.M., Nwabor, O.F., Singh, S., Ontong, J.C., Wunnoo, S., Paosen, S., et al. (2020) Antibacterial-Coated Silk Surgical Sutures by ex Situ Deposition of Silver Nanoparticles Synthesized with Eucalyptus Camaldulensis Eradicates Infections. Journal of Microbiological Methods, 174, Article ID: 105955. [Google Scholar] [CrossRef] [PubMed]
[3] 王晓贺, 徐琳, 付丽. 整合诊疗功能的外科缝合线的研究进展[J]. 应用化学, 2024, 41(10): 1399-1408.
[4] 陈莹, 凃艺辉, 吴高松, 等. 不同缝线对肉芽肿性小叶性乳腺炎术后伤口愈合及美学效果的影响[J]. 组织工程与重建外科, 2022, 18(5): 406-408.
[5] Alabdulkarim, A., Shilash, O.M.B., Alanazi, N.F., Sawad, M.B., Alhusayni, M., Alresheedi, W., et al. (2025) Comparison of Incision Closure in Hand Plastic Surgery Using Non-Absorbable versus Absorbable Sutures: A Systematic Review of Randomized Controlled Trials. Aesthetic Plastic Surgery. [Google Scholar] [CrossRef] [PubMed]
[6] Vakil, A.U., Petryk, N.M., Shepherd, E. and Monroe, M.B.B. (2021) Biostable Shape Memory Polymer Foams for Smart Biomaterial Applications. Polymers, 13, Article 4084. [Google Scholar] [CrossRef] [PubMed]
[7] Claude, O., Grégory, T., Montemagno, S., Bruneval, P. and Masmejean, E. (2007) Vascular Microanastomosis in Rat Femoral Arteries: Experimental Study Comparing Non-Absorbable and Absorbable Sutures. Journal of Reconstructive Microsurgery, 23, 87-91. [Google Scholar] [CrossRef] [PubMed]
[8] 陆远, 王祺, 王煦, 等. 医用缝合线纤维材料发展及应用[J]. 合成材料老化与应用, 2022, 51(3): 140-142.
[9] 胡煜雯. 不同可吸收性外科缝线的介绍和降解研究[J]. 中国医疗器械信息, 2019, 25(5): 50-51, 165.
[10] Byrne, M. and Aly, A. (2019) The Surgical Suture. Aesthetic Surgery Journal, 39, S67-S72. [Google Scholar] [CrossRef] [PubMed]
[11] Pillai, C.K.S. and Sharma, C.P. (2010) Review Paper: Absorbable Polymeric Surgical Sutures: Chemistry, Production, Properties, Biodegradability, and Performance. Journal of Biomaterials Applications, 25, 291-366. [Google Scholar] [CrossRef] [PubMed]
[12] 王东敏, 马佩芬, 王永刚, 等. 壳聚糖/纳米金可吸收抗菌手术缝线的研发及应用研究[Z]. 兰州: 西北民族大学, 2020-07-15.
[13] Wang, X., Kluge, J.A., Leisk, G.G. and Kaplan, D.L. (2008) Sonication-induced Gelation of Silk Fibroin for Cell Encapsulation. Biomaterials, 29, 1054-1064. [Google Scholar] [CrossRef] [PubMed]
[14] 耿劲松, 冯哲, 鲍海妮, 等. 三氯生涂层缝线预防手术部位感染的效果评估[J]. 中国卫生资源, 2022, 25(2): 181-187.
[15] 王秀婷. 四种缝线在口腔软组织缝合应用效果的对比[D]: [硕士学位论文]. 大连: 大连医科大学, 2020.
[16] Dong, Z., Miao, Y., Cui, H., Huang, Q., Li, Y. and Wang, Z. (2021) Structural Evolution of Polyglycolide and Poly(Glycolide-co-Lactide) Fibers during the Heat-Setting Process. Biomacromolecules, 22, 3342-3356. [Google Scholar] [CrossRef] [PubMed]
[17] Nezhentsev, A., Abhari, R.E., Baldwin, M.J., Mimpen, J.Y., Augustyniak, E., Isaacs, M., et al. (2021) In Vitro Evaluation of the Response of Human Tendon‐Derived Stromal Cells to a Novel Electrospun Suture for Tendon Repair. Translational Sports Medicine, 4, 409-418. [Google Scholar] [CrossRef] [PubMed]
[18] 李燕书, 王海刚, 孟繁杰, 等. 不同缝线在腹腔镜下疝囊高位结扎治疗小儿斜疝的比较[J]. 中国微创外科杂志, 2013, 13(10): 879-880.
[19] 齐桓, 付晓幼. 医用尼龙线和改良软尿道扩张器在防治后尿道狭窄的应用[J]. 南方医科大学学报, 2006, 26(3): 369-370.
[20] Manfredini, M., Ferrario, S., Beretta, P., Farronato, D. and Poli, P.P. (2022) Evaluation of Breaking Force of Different Suture Materials Used in Dentistry: An in Vitro Mechanical Comparison. Materials, 15, Article 1082. [Google Scholar] [CrossRef] [PubMed]
[21] 韩蓉. 聚丙烯缝合线的生物安全性评价[D]: [硕士学位论文]. 苏州: 苏州大学, 2010.
[22] 龚光甫, 胡建国, 尹邦良, 等. 膨体聚四氟乙烯缝线替换心瓣膜腱索[J]. 中华胸心血管外科杂志, 1999, 15(6): 333-334.
[23] Matarasso, A. and Ruff, G.L. (2013) The History of Barbed Sutures. Aesthetic Surgery Journal, 33, 12S-16S. [Google Scholar] [CrossRef] [PubMed]
[24] Matarasso, A. and Paul, M.D. (2013) Barbed Sutures in Aesthetic Plastic Surgery: Evolution of Thought and Process. Aesthetic Surgery Journal, 33, 17S-31S. [Google Scholar] [CrossRef] [PubMed]
[25] 王旭晨, 吴沁婷, 郑兆柱, 等. 医用缝合线的研究进展[J]. 安徽工程大学学报, 2020, 35(5): 1-11.
[26] Matarasso, A., Hurwitz, D.J. and Reuben, B. (2013) Quill Barbed Sutures in Body Contouring Surgery: A 6-Year Comparison with Running Absorbable Braided Sutures. Aesthetic Surgery Journal, 33, 44S-56S. [Google Scholar] [CrossRef] [PubMed]
[27] Einarsson, J.I., Chavan, N.R., Suzuki, Y., Jonsdottir, G., Vellinga, T.T. and Greenberg, J.A. (2011) Use of Bidirectional Barbed Suture in Laparoscopic Myomectomy: Evaluation of Perioperative Outcomes, Safety, and Efficacy. Journal of Minimally Invasive Gynecology, 18, 92-95. [Google Scholar] [CrossRef] [PubMed]
[28] 李亚东, 李旺勇, 孙杰, 等. 可吸收单向倒刺缝线在老年腹腔镜胆总管一期缝合术51例中的应用[J]. 安徽医药, 2022, 26(7): 1364-1367.
[29] 陈立彬, 陈宗安, 马倩玉, 等. 免打结倒刺缝线在瘢痕整形手术中的应用[J]. 组织工程与重建外科, 2021, 17(1): 41-43.
[30] Scognamiglio, F., Travan, A., Rustighi, I., Tarchi, P., Palmisano, S., Marsich, E., et al. (2015) Adhesive and Sealant Interfaces for General Surgery Applications. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 104, 626-639. [Google Scholar] [CrossRef] [PubMed]
[31] Ferrao, P., Mohideen, M. and Frey, C. (2008) Liquiband Surgical Tissue Adhesive Compared to Conventional Wound Management. Orthopaedic Proceedings, 90-B, 466.
[32] 李霜, 张娟. Dermabond皮肤粘合剂对外科手术切口愈合效果及美观度的影响[J]. 中国美容医学, 2020, 29(1): 134-136.

为你推荐