纳米骨生物材料在骨组织工程中的研究现状和展望
Current Research Status and Prospects of Nano Bone Biomaterials in Bone Tissue Engineering
DOI: 10.12677/ms.2025.153047, PDF,    科研立项经费支持
作者: 张 昊, 张树琢, 戴鸿浩, 刘志斌, 黄俊龙：青海大学临床医学院，青海 西宁；青海省人民医院骨三科，青海 西宁；单中书*：青海省人民医院骨三科，青海 西宁
关键词: 纳米结构；骨生物材料；骨组织工程；生物活性；Nanostructures； Bone Biomaterials； Bone Tissue Engineering； Bioactivity
摘要: 骨缺损是临床急需解决的热点和难点，骨组织工程的应用发挥重要的作用，其中纳米骨生物材料因其独特的物理化学性质和促骨再生和修复的生物性能方面展现出巨大潜力。本文综述了不同纳米骨生物材料(如纳米羟基磷灰石、碳纳米管、石墨烯、纳米纤维等)在骨组织工程的应用研究现状。通过对这些材料的理化特性、材料结构和力学性能及生物活性的对比分析和在骨组织工程中的应用，旨在纳米骨材料的选择和复合骨材料研发设计提供新的研究展望。
Abstract: Bone defects represent a significant challenge and urgent issue in clinical practice. Bone tissue engineering plays a critical role in addressing this problem, with nano bone biomaterials showing great potential due to their unique physicochemical properties and their biological performance in promoting bone regeneration and repair. This paper reviews the current research status of various nano bone biomaterials, including nano-hydroxyapatite, carbon nanotubes, graphene, and nanofibers, in bone tissue engineering. Through comparative analysis of these materials’ physicochemical properties, structural and mechanical characteristics, and bioactivity, as well as their applications in bone tissue engineering, this review aims to provide new perspectives for the selection of nano bone materials and the development and design of composite bone materials.
文章引用：张昊, 张树琢, 戴鸿浩, 刘志斌, 黄俊龙, 单中书. 纳米骨生物材料在骨组织工程中的研究现状和展望[J]. 材料科学, 2025, 15(3): 410-422. https://doi.org/10.12677/ms.2025.153047

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