改良经肋软骨膜入路胸腹神经阻滞的研究进展
Research Advances in Modified Thoracoabdominal Nerves Block through Perichondrial Approach
DOI: 10.12677/acm.2025.154913, PDF,   
作者: 陈官涛:大理大学临床医学院,云南 大理;杨永菊:云南省滇东北中心医院麻醉科,云南 昭通;张 敏, 刘 云, 吕建鸿, 唐玲玲*:云南省第三人民医院麻醉科,云南 昆明
关键词: 改良经肋软骨入路胸腹神经阻滞多模式镇痛超声引导神经阻滞腹部手术Modified Thoracoabdominal Nerves Block through Perichondrial Approach Multimodal Analgesia Ultrasound Guidance Nerve Block Abdominal Surgery
摘要: 改良经肋软骨膜入路胸腹神经阻滞(modified thoracoabdominal nerves block through perichondrial approach, M-TAPA)是一种为腹部手术提供良好镇痛的筋膜平面阻滞技术,有研究表明M-TAPA可以有效减轻各类腹部手术围术期疼痛,是围术期多模式镇痛的新选择。本文回顾近年来国内外对超声引导下M-TAPA的研究,对其解剖定位、作用机制、用药选择、阻滞范围、临床应用及技术优势等方面进行综述,旨在为临床应用提供参考。
Abstract: The modified thoracoabdominal nerves block through perichondrial approach (M-TAPA) is a fascial plane block technique that offers effective analgesia for patients undergoing abdominal surgery. Research indicates that M-TAPA can significantly reduce perioperative pain in a variety of abdominal procedures, presenting itself as a new option for multimodal analgesic regimens in the perioperative period. This article conducts a comprehensive review of recent domestic and international studies on ultrasound-guided M-TAPA, elucidating its anatomical landmarks, mechanism of action, pharmacological considerations, block extent, clinical applications, and technical benefits. The aim is to serve as a valuable resource for clinicians considering the integration of this technique into their practice.
文章引用:陈官涛, 杨永菊, 张敏, 刘云, 吕建鸿, 唐玲玲. 改良经肋软骨膜入路胸腹神经阻滞的研究进展[J]. 临床医学进展, 2025, 15(4): 155-162. https://doi.org/10.12677/acm.2025.154913

参考文献

[1] 曹晖, 陈亚进, 顾小萍, 等. 中国加速康复外科临床实践指南(2021版) [J]. 中国实用外科杂志, 2021, 41(9): 961-992.
[2] Chin, K.J., McDonnell, J.G., Carvalho, B., Sharkey, A., Pawa, A. and Gadsden, J. (2017) Essentials of Our Current Understanding: Abdominal Wall Blocks. Regional Anesthesia and Pain Medicine, 42, 133-183. [Google Scholar] [CrossRef
[3] Tulgar, S., Senturk, O., Selvi, O., Balaban, O., Ahiskalioğlu, A., Thomas, D.T., et al. (2019) Perichondral Approach for Blockage of Thoracoabdominal Nerves: Anatomical Basis and Clinical Experience in Three Cases. Journal of Clinical Anesthesia, 54, 8-10. [Google Scholar] [CrossRef] [PubMed]
[4] Tanaka, N., Suzuka, T., Kadoya, Y., Okamoto, N., Sato, M., Kawanishi, H., et al. (2022) Efficacy of Modified Thoracoabdominal Nerves Block through Perichondrial Approach in Open Gynecological Surgery: A Prospective Observational Pilot Study and a Cadaveric Evaluation. BMC Anesthesiology, 22, Article No. 107. [Google Scholar] [CrossRef] [PubMed]
[5] Sawada, A., Kumita, S., Nitta, A., Ohsaki, Y. and Yamakage, M. (2023) Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA): An Anatomical Study to Evaluate the Spread of Dye after a Simulated Injection in Soft Embalmed Thiel Cadavers. Regional Anesthesia & Pain Medicine, 48, 403-407. [Google Scholar] [CrossRef] [PubMed]
[6] Tulgar, S., Selvi, O., Thomas, D.T., Deveci, U. and Özer, Z. (2019) Modified Thoracoabdominal Nerves Block through Perichondrial Approach (M-TAPA) Provides Effective An-algesia in Abdominal Surgery and Is a Choice for Opioid Sparing Anesthesia. Journal of Clinical Anesthesia, 55, 109. [Google Scholar] [CrossRef] [PubMed]
[7] Bilge, A., Başaran, B., Et, T., Korkusuz, M., Yarımoğlu, R., Toprak, H., et al. (2022) Ultrasound-Guided Bilateral Modified-Thoracoabdominal Nerve Block through a Perichondrial Approach (M-TAPA) in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Double-Blind Controlled Trial. BMC Anesthesiology, 22, Article No. 329. [Google Scholar] [CrossRef] [PubMed]
[8] 赵聪, 尹泓, 蔡敏, 等. 改良经肋软骨膜入路胸腹神经阻滞与腹横肌平面阻滞用于腹腔镜袖状胃切除术的比较[J]. 临床麻醉学杂志, 2022, 38(6): 569-573.
[9] Bilge, A., Başaran, B., Altıparmak, B., Et, T., Korkusuz, M. and Yarımoğlu, R. (2023) Comparing Ultrasound-Guided Modified Thoracoabdominal Nerves Block through Perichondrial Approach with Oblique Subcostal Transversus Abdominis Plane Block for Patients Undergoing Laparoscopic Cholecystectomy: A Randomized, Controlled Trial. BMC Anesthesiology, 23, Article No. 139. [Google Scholar] [CrossRef] [PubMed]
[10] Gurbuz, H., Ekinci, M. and Kaciroglu, A. (2024) Modified Thoracoabdominal Nerves Block through Perichondrial Approach (M‐TAPA) for Nephrectomy in Children. Pediatric Anesthesia, 34, 1162-1164. [Google Scholar] [CrossRef] [PubMed]
[11] Ozen, V., Acik, M.E. and Ozen, N. (2023) The Modified Thoracoab-dominal Nerve Block for Post-Operative Analgesia in Paediatric Laparoscopic Cholecystectomy. Journal of Minimal Ac-cess Surgery, 20, 452-455. [Google Scholar] [CrossRef] [PubMed]
[12] Suzuka, T., Tanaka, N., Kadoya, Y., Ida, M., Iwata, M., Ozu, N., et al. (2024) Comparison of Quality of Recovery between Modified Thoracoabdominal Nerves Block through Perichondrial Approach versus Oblique Subcostal Transversus Abdominis Plane Block in Patients Undergoing Total Laparoscopic Hysterectomy: A Pilot Randomized Controlled Trial. Journal of Clinical Medicine, 13, Article 712. [Google Scholar] [CrossRef] [PubMed]
[13] Heppolette, C.A.A., Brunnen, D., Bampoe, S. and Odor, P.M. (2020) Clinical Pharmacokinetics and Pharmacodynamics of Levobupivacaine. Clinical Pharmacokinetics, 59, 715-745. [Google Scholar] [CrossRef] [PubMed]
[14] Aikawa, K., Uchinami, Y. and Morimoto, Y. (2023) Chronolog-ical Changes in Plasma Levobupivacaine Concentrations after Bilateral Modified Thoracoabdominal Nerve Block through Perichondrial Approach. Journal of Anesthesia, 37, 641-644. [Google Scholar] [CrossRef] [PubMed]
[15] Hirai, N., Tanaka, N., Suzuka, T., Kadoya, Y. and Kawaguchi, M. (2023) Letter to the Editor Regarding ‘Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA): An Anatomical Study Evaluating Dye Spread Following Simulated Injection in Soft Embalmed Thiel Ca-daver’. Regional Anesthesia & Pain Medicine, 49, 376-377. [Google Scholar] [CrossRef] [PubMed]
[16] Ciftci, B., Alici, H.A., Ansen, G., Sakul, B.U. and Tulgar, S. (2022) Cadaveric Investigation of the Spread of the Thoracoab-dominal Nerve Block Using the Perichondral and Modified Perichondral Approaches. Korean Journal of Anesthesiology, 75, 357-359. [Google Scholar] [CrossRef] [PubMed]
[17] Altıparmak, B., Korkmaz Toker, M., Uysal, A.İ., Turan, M. and Gümüş Demirbilek, S. (2019) The Successful Usage of Modified Thoracoabdominal Nerves Block through Peri-chondrial Approach (M-TAPA) for Analgesia of Laparoscopic Ventral Hernia Repair. Journal of Clinical Anesthesia, 57, 1-2. [Google Scholar] [CrossRef] [PubMed]
[18] Ohgoshi, Y., Kawagoe, I., Ando, A., Ikegami, M., Hanai, S. and Ichimura, K. (2022) Novel External Oblique Muscle Plane Block for Blockade of the Lateral Abdominal Wall: A Pilot Study on Volunteers. Canadian Journal of Anesthesia/Journal canadien d’anesthésie, 69, 1203-1210. [Google Scholar] [CrossRef] [PubMed]
[19] Aikawa, K., Tanaka, N. and Morimoto, Y. (2020) Modified Thoracoabdominal Nerves Block through Perichondrial Approach (M-TAPA) Provides a Sufficient Postoperative Anal-gesia for Laparoscopic Sleeve Gastrectomy. Journal of Clinical Anesthesia, 59, 44-45. [Google Scholar] [CrossRef] [PubMed]
[20] Aikawa, K., Yokota, I., Maeda, Y. and Morimoto, Y. (2021) Evaluation of Sensory Loss Obtained by Modified-Thoracoabdominal Nerves Block through Perichondrial Approach in Patients Undergoing Gynecological Laparoscopic Surgery: A Prospective Observational Study. Regional Anesthesia & Pain Medicine, 47, 134-135. [Google Scholar] [CrossRef] [PubMed]
[21] Matsuura, H., Terada, Y., Rokkaku, Y., Tamagawa, H., Taniguchi, E., Saito, Y., et al. (2023) Analgesic Efficacy of Modified Thoracoabdominal Nerves Block through the Perichondrial Approach in Laparoscopic Cholecystectomy: A Retrospective Study with Propensity Analysis. Asian Journal of Endo-scopic Surgery, 16, 648-652. [Google Scholar] [CrossRef] [PubMed]
[22] 陈燕琪, 马晓彤, 夏佳怡, 等. 改良经肋软骨周入路胸腹部神经阻滞在肥胖患者腹腔镜袖状胃切除术中的应用[J]. 医学研究杂志, 2021, 50(4): 128-131.
[23] Avci, O., Gundogdu, O., Balci, F. and Tekcan, M.N. (2024) Effects of Modified Thoracoabdominal Nerve Block through Perichondrial Approach on Postoperative Pain and Analgaesic Consumption in Patients Undergoing Laparoscopic Cholecystectomy. Journal of the College of Physicians and Surgeons Pakistan, 34, 5-10.
[24] de Oliveira, E.J.S.G., De Lima, R.C., Sakata, R.K., Freire, T.T., de Almeida Lima, E.L., de Oliveira, C.M.B., et al. (2021) Modified Thoracoabdominal Nerve Block through the Perichondral Approach (M-TAPA) in Laparoscopic Sleeve Gastroplasty: A Case Series. Obesity Surgery, 32, 197-201. [Google Scholar] [CrossRef] [PubMed]
[25] Alver, S., Ciftci, B., Güngör, H., Gölboyu, B.E., Ozdenkaya, Y., Alici, H.A., et al. (2023) Efficacy of Modified Thoracoabdominal Nerve Block through Perichondrial Approach Following Laparoscopic Inguinal Hernia Repair Surgery: A Randomized Controlled Trial. Brazilian Journal of Anesthesiology (English Edition), 73, 595-602. [Google Scholar] [CrossRef] [PubMed]
[26] Ohgoshi, Y., Ando, A., Kawamata, N. and Kubo, E.N. (2020) Continuous Modified Thoracoabdominal Nerves Block through Perichondrial Approach (M-TAPA) for Major Ab-dominal Surgery. Journal of Clinical Anesthesia, 60, 45-46. [Google Scholar] [CrossRef] [PubMed]
[27] Prabhakar, A., Ward, C.T., Watson, M., Sanford, J., Fiza, B., Moll, V., et al. (2019) Liposomal Bupivacaine and Novel Local Anesthetic Formulations. Best Practice & Research Clinical Anaesthesiology, 33, 425-432. [Google Scholar] [CrossRef] [PubMed]
[28] Luo, J., Duan, G., Huang, H. and Chen, G. (2024) Research Status of Different Adjuvants on Nerve Block’s Effect. Pain Physician Journal, 27, 507-519. [Google Scholar] [CrossRef
[29] Nakahari, H., Takahashi, T., Miki, H. and Yamaguchi, A. (2024) Postoperative Analgesia with Modified Thoracoabdominal Nerve Block through Perichondrial Approach in Neonatal and Infantile Abdominal Surgery. Cureus, 16, e65219. [Google Scholar] [CrossRef] [PubMed]
[30] Et, T. and Korkusuz, M. (2024) Modified Thoracoabdominal Perichon-drial Approach (M-TAPA) Injections with Bupivacaine and Dexamethasone on Treatment of Postherpetic Neuralgia. Minerva Anestesiologica, 90, 467-468. [Google Scholar] [CrossRef] [PubMed]
[31] 王小平, 舒海华, 黄雪花, 等. 腹横肌平面阻滞中国疼痛学与麻醉学专家共识(2023版) [J]. 中华疼痛学杂志, 2023, 19(2): 184-201.
[32] Zhang, A.Z., Ficklscherer, A., Gü-lecyüz, M.F., Paulus, A.C., Niethammer, T.R., Jansson, V., et al. (2017) Cell Toxicity in Fibroblasts, Tenocytes, and Human Mesenchymal Stem Cells—A Comparison of Necrosis and Apoptosis-Inducing Ability in Ropivacaine, Bupiva-caine, and Triamcinolone. Arthroscopy: The Journal of Arthroscopic & Related Surgery, 33, 840-848. [Google Scholar] [CrossRef] [PubMed]
[33] Güngör, H., Ciftci, B., Alver, S., Gölboyu, B.E., Ozdenkaya, Y. and Tulgar, S. (2022) Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) vs Local Infiltration for Pain Management after Laparoscopic Cholecystectomy Surgery: A Randomized Study. Journal of Anes-thesia, 37, 254-260. [Google Scholar] [CrossRef] [PubMed]
[34] Castillo-Dávila, L.F., Torres-Anaya, C.J., Vazquez-Apodaca, R., Borboa-Olivares, H., Espino-y-Sosa, S. and Torres-Torres, J. (2024) Modified Thoracoabdominal Nerve Block via Per-ichondral Approach: An Alternative for Perioperative Pain Management in Laparoscopic Cholecystectomy in a Mid-dle-Income Country. BMC Anesthesiology, 24, Article No. 304. [Google Scholar] [CrossRef] [PubMed]