白色中心视网膜出血的研究进展
Research Progress on White-Centered Retinal Hemorrhage
DOI: 10.12677/acm.2025.154929, PDF,   
作者: 何 聪, 叶振伟, 赵 恬：暨南大学附属爱尔眼科医院，眼科，广东 广州；张艳莉*：暨南大学附属爱尔眼科医院，眼科，广东 广州；中山爱尔眼科医院，眼科，广东 中山
关键词: 白色中心视网膜出血；Roth斑；感染性心内膜炎；White-Centered Retinal Hemorrhage； Roth Spots； Infective Endocarditis
摘要: 白色中心视网膜出血(WCRH)是指视网膜出血点中央出现黄白色或淡黄色斑点，曾被认为是一种特征性的视网膜出血，通常发生于感染性心内膜炎，又被称为Roth斑，但逐渐在其他疾病中发现了踪影。包括白血病、恶性贫血、婴儿摇晃综合症、艾滋病、一氧化碳中毒等。鉴于临床实践中对该体征的认知尚存不足，本文旨在介绍Roth斑发病机制及临床意义。
Abstract: White-centered retinal hemorrhage (WCRH), characterized by a pale yellow or yellow-white spot in the center of a retinal hemorrhage, was once considered a distinctive type of retinal hemorrhage typically associated with infective endocarditis, also known as Roth spots. However, it has gradually been identified in other diseases as well. These include hematologic disorders, other infectious diseases, retinal vasculitis, trauma, and hypoxia. This article aims to explore the historical background of Roth spots, the current understanding of their pathogenesis, and their clinical significance.
文章引用：何聪, 叶振伟, 赵恬, 张艳莉. 白色中心视网膜出血的研究进展[J]. 临床医学进展, 2025, 15(4): 268-274. https://doi.org/10.12677/acm.2025.154929

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