输尿管结石治疗中应用超声下体外冲击波碎石术联合坦索罗辛的疗效

Therapeutic Effect of Ultrasound Combined with Extracorporeal Shock Wave Lithotripsy and Tamsulosin in the Treatment of Ureteral Calculi

摘要: 目的：探讨输尿管结石治疗中应用超声下体外冲击波碎石术联合坦索罗辛的疗效。方法：回顾选取本院2023.6~2024.6期间收治的66例输尿管结石患者。之后对比两组患者的炎症指标、术后疼痛、排尿参数、治疗效果与并发症发生率、生活质量、长期预后效果及结石复发率。结果：观察组患者CRP、LL-6、TNF-α的炎症指标较优(P < 0.05)；观察组患者术后疼痛数据较优(P < 0.05)；观察组患者排尿参数在治疗后明显低于对照组(P < 0.05)；观察组患者治疗效果、并发症发生率优于对照组(P < 0.05)；观察组患者生活质量数据较优(P < 0.05)；观察组患者长期预后效果及结石复发率优于对照组(P < 0.05)。结论：输尿管结石的临床治疗中，可将超声下体外冲击波碎石与坦索罗辛配合使用，实现降低炎症指标、提高排石效果、改善患者生活质量的目标，且长期预后效果显著，复发率较低，值得临床广泛推广。

Abstract: Objective: To investigate the efficacy of ultrasound combined with extracorporeal shock wave lithotripsy and tamsulosin in the treatment of ureteral stones. Method: A retrospective analysis was conducted on 66 patients with ureteral stones admitted to our hospital between June 2023 and June 2024. After that, the inflammation index, postoperative pain, micturition parameters, treatment effect and complication rate, quality of life, long-term prognosis effect and stone recurrence rate of the two groups were compared. Results: The inflammatory indicators of CRP, LL-6, and TNF-α in the observation group were better (P < 0.05); The postoperative pain data of the observation group patients were better (P < 0.05); The urinary parameters of the observation group patients were significantly lower than those of the control group after treatment (P < 0.05); The treatment effect and incidence of complications in the observation group were better than those in the control group (P < 0.05); The quality of life data of the observation group patients was better (P < 0.05); The long-term prognosis and recurrence rate of stones in the observation group were better than those in the control group (P < 0.05). Conclusion: In the clinical treatment of ureteral stones, ultrasound assisted extracorporeal shock wave lithotripsy can be combined with tamsulosin to achieve the goals of reducing inflammatory indicators, improving stone removal efficiency, and enhancing patients’ quality of life. And the long-term prognosis effect is remarkable, and the recurrence rate is low, which is worth popularizing widely in clinic.