青少年女性卵巢类固醇细胞肿瘤1例诊疗体会并文献复习

Diagnosis and Treatment Experience of 1 Case of Ovarian Steroid Cell Tumor in Adolescent Females and Literature Review

摘要: 青岛大学附属医院妇科收治的1例青少年女性卵巢类固醇细胞瘤患者临床病例回顾性分析。青年女性，既往月经规律，近1年来无明显诱因出现月经不规则，月经期延长至15~20天，月经周期及月经量无明显改变，超声检查提示左侧卵巢肿瘤直径约2 cm，未予治疗，后定期复查彩色多普勒超声提示包块逐渐增大。为求进一步治疗于2024年7月来青岛大学附属医院妇科就诊。B超检查提示左附件区5.1 × 4.5 × 4.3 cm混合回声团，考虑卵巢畸胎瘤，行腹腔镜下左侧卵巢肿瘤剥除术，术后病理检查提示左侧卵巢类固醇细胞肿瘤。该病的治疗方法最主要的是手术方式也需要根据患者的年龄和生育要求而定。辅助检查通过激素测定和影像学相关检查提供重要的参考依据，使疾病得以诊断。通过这一病例的报告，加强对卵巢肿瘤疾病的了解。

Abstract: A Retrospective Clinical Analysis of an Adolescent Female with Ovarian Steroid Cell Tumor Treated at the Department of Gynecology, Affiliated Hospital of Qingdao University. The patient, a young female with previously regular menstruation, developed irregular menstrual cycles over the past year without identifiable triggers, characterized by prolonged menstrual periods lasting 15~20 days, while menstrual cycle intervals and flow remained unchanged. Initial ultrasound revealed a left ovarian tumor measuring approximately 2 cm in diameter, which was monitored without intervention. Subsequent follow-up color Doppler ultrasound examinations demonstrated gradual enlargement of the mass. Seeking further treatment, the patient presented to the Department of Gynecology at the Affiliated Hospital of Qingdao University in July 2024. Ultrasound imaging identified a mixed-echo mass (5.1 × 4.5 × 4.3 cm) in the left adnexal region, suggestive of ovarian teratoma. Laparoscopic left ovarian tumor resection was performed, with postoperative histopathological examination confirming a left ovarian steroid cell tumor. The primary treatment for this condition is surgical intervention, with the specific approach tailored to the patient’s age and fertility requirements. Auxiliary diagnostic evaluations, including hormonal assays and imaging studies, provide critical reference information for diagnosis. This case report enhances the understanding of ovarian tumor diseases.