儿童骨和软骨肉瘤:诊断及治疗的新型进展和未来方向
Pediatric Osteosarcoma and Chondrosarcoma: Recent Advances and Future Directions in Diagnosis and Treatment
DOI: 10.12677/acm.2025.1541125, PDF,    科研立项经费支持
作者: 石明艳, 刘 星*:重庆医科大学附属儿童医院骨科,国家儿童健康与疾病临床医学研究中心,中国儿童发育与危重症国际科技合作基地,重庆;钟世民:重庆市第七人民医院(重庆理工大学附属中心医院)儿科,重庆
关键词: 儿童骨肉瘤软骨肉瘤诊断治疗Children Osteosarcoma Chondrosarcoma Diagnosis Treatment
摘要: 原发性骨肿瘤(Primary bone sarcomas)是一类对于临床医生、放射科医生和病理科医生来说难以识别和分类的罕见恶性肿瘤,具有较高的致死率。最常见的原发性骨肿瘤包括骨肉瘤(osteosarcoma)、软骨肉瘤(chondrosarcoma)和尤文肉瘤(Ewing sarcoma)。儿童骨肉瘤和软骨肉瘤已经成为新的儿童原发性骨肿瘤的研究关注焦点,其恶性程度往往较高,预后较差,死亡率较高,因此进行早期诊治非常重要。如何提高骨肉瘤和软骨肉瘤患儿的生存率和生活质量也是目前治疗研究的重点。我们回顾了相关文献,在此试对儿童骨肉瘤和软骨肉瘤现有的诊断和治疗进行分析,对新型相关进展进行述评,以明确临床诊治要点和分析未来发展方向。
Abstract: Primary bone sarcomas are a group of rare malignant tumors can be challenging for clinicians, radiologists, and pathologists to identify and classify, and they are associated with a high mortality rate. The most common primary bone tumors include osteosarcoma, chondrosarcoma, and Ewing sarcoma. Recent research has focused on pediatric osteosarcoma and chondrosarcoma, as these tumors tend to be more aggressive, have a poorer prognosis, and result in a higher mortality rate in children. This underscores the importance of early diagnosis and treatment. Current therapeutic research aims to improve the survival and quality of life for children with osteosarcoma and chondrosarcoma. In this context, we reviewed the relevant literature to analyze the existing methods for diagnosing and treating pediatric osteosarcoma and chondrosarcoma. We will also discuss recent advancements in this field to clarify key points in clinical diagnosis and treatment while exploring future directions for development.
文章引用:石明艳, 钟世民, 刘星. 儿童骨和软骨肉瘤:诊断及治疗的新型进展和未来方向[J]. 临床医学进展, 2025, 15(4): 1814-1823. https://doi.org/10.12677/acm.2025.1541125

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