基于肠道菌群从脾胃论治桥本甲状腺的研究概述

Overview of a Study on the Treatment of Hashimoto’s Thyroid from the Perspective of the Spleen-Stomach Theory Based on Intestinal Flora

摘要: 在中医理论中，桥本甲状腺炎通常被归入“瘿病”、“瘿气”以及“瘿瘤”等范畴之内。作为一种自身免疫性疾病，该病在临床上相对常见，其病程特点是持续时间较长且进展较为缓慢。若未能采取及时且有效的治疗措施，可能会对患者的健康状况造成诸多不利影响。鉴于肠道菌群在疾病演变过程中的重要性日益凸显，并考虑到脾胃作为人体后天发育之根本的生理特征，当前临床研究正兴起一种新趋势，即从脾胃的视角出发，深入探讨相关疾病的病因病理机制，并据此指导治疗策略的制定。文章聚焦于肠道菌群视角，融合理论剖析与临床实践经验，旨在探索运用脾胃调理策略治疗桥本甲状腺炎的有效途径。其主要目标是减轻患者的临床症状，同时维持肠道微生态的平衡，以期为桥本甲状腺疾病的临床预防和治疗提供新的理论视角和实践指导。

Abstract: In Chinese medicine, Hashimoto’s thyroiditis is often categorized as “gall disease,” “gall gas,” and “gall tumor.” As an autoimmune disease, it is relatively common in clinical practice, and its course is characterized by a long duration and slow progression. Failure to take timely and effective therapeutic measures may have many adverse effects on the patient’s health. In view of the increasing importance of intestinal flora in the evolution of diseases, and taking into account the physiological characteristics of the spleen and stomach as the foundation of the human body’s innate development, a new trend in clinical research is emerging, which is to explore the etiological and pathological mechanisms of related diseases from the perspective of the spleen and stomach and to guide the formulation of therapeutic strategies accordingly. This article focuses on the perspective of intestinal flora, integrates theoretical analysis and clinical practice experience, and aims to explore the effective way of treating Hashimoto’s thyroiditis by using spleen and stomach regulating strategies. The main goal is to reduce the clinical symptoms of patients and maintain the balance of intestinal microecology, in order to provide new theoretical perspectives and practical guidance for the clinical prevention and treatment of Hashimoto’s thyroid disease.