病例报告：脊髓损伤患者的恢复——一例非典型脊髓损伤的临床观察
Case Report: Recovery of a Spinal Cord Injury Patient—Clinical Observation on a Case of Atypical Spinal Cord Injury
摘要: 本病例报告描述了一名26岁男性患者，在一次车祸中发生T5~T6胸段脊髓损伤。初步影像学检查确提示T5~T6椎体骨折，损伤水平以下完全丧失运动和感觉功能(ASIA损伤分级A)。尽管初次外科减压手术效果不佳，但通过药物治疗、神经肌肉电刺激(NMES)、以及强化物理治疗的综合干预，患者实现了部分感觉恢复(改善至T8感觉水平)并提高了功能独立性。本案例强调了早期多模式康复对优化完全脊髓损伤患者神经恢复潜力的重要性。
Abstract: This case report describes a 26-year-old male patient who sustained a T5~T6 thoracic spinal cord injury in a traffic accident. Initial imaging studies confirmed vertebral fractures at T5~T6, with complete loss of motor and sensory function below the level of injury (ASIA impairment scale A). Despite the initial surgical decompression being suboptimal, through a comprehensive intervention of pharmacological treatment, neuromuscular electrical stimulation (NMES), and intensive physical therapy, the patient achieved partial sensory recovery (improved to T8 sensory level) and increased functional independence. This case underscores the importance of early multimodal rehabilitation in optimizing the neurologic recovery potential of patients with complete spinal cord injuries.
文章引用：晏露, 叶洁盈, 罗文姬, 陈卓铭. 病例报告：脊髓损伤患者的恢复——一例非典型脊髓损伤的临床观察[J]. 临床医学进展, 2025, 15(4): 2821-2825. https://doi.org/10.12677/acm.2025.1541245

参考文献

[1] Anjum, A., Yazid, M.D., Fauzi Daud, M., Idris, J., Ng, A.M.H., Selvi Naicker, A., et al. (2020) Spinal Cord Injury: Pathophysiology, Multimolecular Interactions, and Underlying Recovery Mechanisms. International Journal of Molecular Sciences, 21, Article No. 7533. [Google Scholar] [CrossRef] [PubMed]
[2] Hu, X., Xu, W., Ren, Y., Wang, Z., He, X., Huang, R., et al. (2023) Spinal Cord Injury: Molecular Mechanisms and Therapeutic Interventions. Signal Transduction and Targeted Therapy, 8, Article No. 245. [Google Scholar] [CrossRef] [PubMed]
[3] Cao, Y., Zhu, S., Yu, B. and Yao, C. (2022) Single‐Cell RNA Sequencing for Traumatic Spinal Cord Injury. The FASEB Journal, 36, e22656. [Google Scholar] [CrossRef] [PubMed]
[4] Liu, K., Dong, X., Wang, Y., Wu, X. and Dai, H. (2022) Dopamine-Modified Chitosan Hydrogel for Spinal Cord Injury. Carbohydrate Polymers, 298, Article ID: 120047. [Google Scholar] [CrossRef] [PubMed]
[5] Quadri, S.A., Farooqui, M., Ikram, A., Zafar, A., Khan, M.A., Suriya, S.S., et al. (2018) Recent Update on Basic Mechanisms of Spinal Cord Injury. Neurosurgical Review, 43, 425-441. [Google Scholar] [CrossRef] [PubMed]
[6] Karamian, B.A., Siegel, N., Nourie, B., Serruya, M.D., Heary, R.F., Harrop, J.S., et al. (2022) The Role of Electrical Stimulation for Rehabilitation and Regeneration after Spinal Cord Injury. Journal of Orthopaedics and Traumatology, 23, Article No. 2. [Google Scholar] [CrossRef] [PubMed]
[7] Rao, S. and Treggiari, M.M. (2021) Anesthesia for Acute Spinal Cord Injury. Anesthesiology Clinics, 39, 127-138. [Google Scholar] [CrossRef] [PubMed]
[8] Fehlings, M.G., Wilson, J.R., Harrop, J.S., Kwon, B.K., Tetreault, L.A., Arnold, P.M., et al. (2017) Efficacy and Safety of Methylprednisolone Sodium Succinate in Acute Spinal Cord Injury: A Systematic Review. Global Spine Journal, 7, 116S-137S. [Google Scholar] [CrossRef] [PubMed]
[9] Walters, B.C. (2013) Methodology of the Guidelines for the Management of Acute Cervical Spine and Spinal Cord Injuries. Neurosurgery, 72, 17-21. [Google Scholar] [CrossRef] [PubMed]
[10] Sherrod, B., Karsy, M., Guan, J., Brock, A.A., Eli, I.M., Bisson, E.F., et al. (2019) Spine Trauma and Spinal Cord Injury in Utah: A Geographic Cohort Study Utilizing the National Inpatient Sample. Journal of Neurosurgery: Spine, 31, 93-102. [Google Scholar] [CrossRef] [PubMed]
[11] Pelletier, C. (2023) Exercise Prescription for Persons with Spinal Cord Injury: A Review of Physiological Considerations and Evidence-Based Guidelines. Applied Physiology, Nutrition, and Metabolism, 48, 882-895. [Google Scholar] [CrossRef] [PubMed]

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