中药在糖尿病肾病治疗中的研究进展
Research Progress of Traditional Chinese Medicine in the Treatment of Diabetic Nephropath
摘要: 糖尿病肾病作为糖尿病最主要的微血管并发症之一，是由多基因调控异常引发的复杂慢性疾病，其病理进展可导致终末期肾病(ESRD)及患者死亡。当前西医治疗但临床实践中仍面临严峻挑战，中医药因其多靶点调控特性成为极具潜力的替代疗法。然而，现有研究在机制阐释、剂量标准化及临床转化方面仍存不足。本文系统综述DN的病理机制及中药干预进展，旨在整合基础实验与临床研究证据，为开发基于中医药理论的DN精准治疗方案提供理论支撑。
Abstract: Diabetic nephropathy, as one of the most significant microvascular complications of diabetes, is a complex chronic disease caused by abnormal regulation of multiple genes. Its pathological progression can lead to end-stage renal disease (ESRD) and the death of patients. At present, Western medicine still faces severe challenges in clinical practice. Traditional Chinese medicine, due to its multi-target regulatory characteristics, has become a highly potential alternative therapy. However, the existing studies still have deficiencies in mechanism interpretation, dose standardization and clinical transformation. This article systematically reviews the pathological mechanism of DN and the progress of traditional Chinese medicine intervention, aiming to integrate the evidence from basic experiments and clinical research, and provide theoretical support for the development of precise treatment plans for DN based on the theory of traditional Chinese medicine.
文章引用：刘梦实, 池海谊, 王平. 中药在糖尿病肾病治疗中的研究进展[J]. 临床医学进展, 2025, 15(4): 3060-3069. https://doi.org/10.12677/acm.2025.1541272

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