SMILE与FS-LASIK对低中度近视患者眼底结构的差异

Difference of Fundus Structure between SMILE and FS-LASIK in Patients with Low to Moderate Myopia

摘要: 目的：采用SS-OCT探讨低中度近视患者行SMILE或FS-LASIK术后眼底微血管结构的差异。方法：选择行SMILE或FS-LASIK的低中度近视患者；使用SS-OCT分别于术前，术后1天、1月、3月测量以黄斑和视盘为中心各区域的CT、CVI、CVV、FAZ。结果：1) FS-LASIK组负压时间低于SMILE组(P < 0.05)。2) FAZ组间比较两组术后各随访点无差异。3) 黄斑区组间比较：以黄斑为中心各区域的CT、CVV、CV两组各随访点均无差异。4) 视盘区组间比较：① CT：视盘区FS-LASIK组术后各随访点均低于SMILE组(P < 0.05)；视盘旁区两组各随访点无差异。② CVV：视盘区FS-LASIK组术后各随访点均低于SMILE组(P < 0.05)；视盘旁区两组均无差异。③ CVI：视盘区及视盘旁区两组术后各随访点均无差异。结论：SMILE和FS-LASIK对低中度近视患者眼底微血管结构是同等安全的。

Abstract: Objective: To investigate the difference of fundus microvascular structure in patients with low to moderate myopia after SMILE or FS-LASIK by SS-OCT. Methods: Patients with low to moderate myopia who underwent SMILE or FS-LASIK were selected. SS-OCT was used to measure CT, CVI, CVV and FAZ in each area centered on macula and optic disc before surgery, 1 day, 1 month and 3 months after surgery, respectively. Results: 1) The negative pressure time of FS-LASIK group was lower than that of SMILE group (P < 0.05). 2) Comparison between FAZ groups showed no difference in follow-up points between the two groups. 3) Comparison between groups in macular area: There were no differences in CT, CVV and CV at each follow-up point in each area centered on macular area. 4) Comparison between the groups: ① The number of follow-up points in CT: FS-LASIK group was lower than that in SMILE group (P < 0.05); There was no difference between the two groups at each follow-up point. ② CVV: all follow-up points in FS-LASIK group were lower than those in SMILE group (P < 0.05). There was no difference in the paratopic area between the two groups. ③ CVI: There was no difference in follow-up points between the two groups in the optic disc area and the paroptic disc area. Conclusion: SMILE and FS-LASIK are equally safe for fundus microvascular structure in patients with low to moderate myopia.