急性胰腺炎及相关急性呼吸窘迫综合征发病机制的研究进展
Research Progress on the Pathogenesis of Acute Pancreatitis and Related Acute Respiratory Distress Syndrome
DOI: 10.12677/acm.2025.1541320, PDF,    科研立项经费支持
作者: 甘小冰, 苏红羽, 李业芳, 张若男：承德医学院研究生学院，河北 承德；陈治国*：承德市中心医院急诊科，河北 承德
关键词: 急性胰腺炎；急性呼吸窘迫综合症；发病机制；免疫反应；肠道菌群；Acute Pancreatitis； Acute Respiratory Distress Syndrome； Pathogenesis； Immune Response； Intestinal Microbiota
摘要: 急性胰腺炎(AP)是临床常见急腹症之一，部分患者经内科积极治疗后仍会发展为重症急性胰腺炎(SAP)，并伴有持续性器官衰竭。肺脏是SAP最常累及的胰腺外器官之一，其中急性呼吸窘迫综合征(ARDS)是SAP最常见且最严重的并发症之一，死亡率较高。但目前关于AP及AP相关ARDS的发病机制尚不明确，仍需进一步深入研究。了解疾病的发病机制有助于更好的管理和治疗。本文就AP及相关ARDS发病机制方面的研究进展进行综述，以期增加对疾病的认识，为找到更有效的预防和治疗方法提供思路。
Abstract: Acute pancreatitis (AP) is one of the common clinical acute abdomen. Some patients will develop into severe acute pancreatitis (SAP) even after active medical treatment, accompanied by persistent organ failure. Lung is one of the most common extrapancreatic organs involved in SAP. Among them, acute respiratory distress syndrome (ARDS) is one of the most common and serious complications of SAP, with a high mortality rate. However, the pathogenesis of AP and AP-related ARDS is still unclear, and further research is needed. Understanding the pathogenesis of the disease is helpful for better management and treatment. This article reviews the research progress on the pathogenesis of AP and related ARDS, in order to increase the understanding of the disease and provide ideas for finding more effective prevention and treatment methods.
文章引用：甘小冰, 苏红羽, 李业芳, 张若男, 陈治国. 急性胰腺炎及相关急性呼吸窘迫综合征发病机制的研究进展[J]. 临床医学进展, 2025, 15(4): 3472-3481. https://doi.org/10.12677/acm.2025.1541320

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