壳聚糖用于骨支架研究进展
Research Progress of Chitosan as Bone Scaffold
DOI: 10.12677/acm.2025.1541323, PDF,   
作者: 方佳瑶, 张 帅*, 何 铮, 汪丽雯:浙江中医药大学口腔医学院,浙江 杭州
关键词: 壳聚糖骨支架骨组织工程复合材料Chitosan Bone Scaffold Bone Tissue Engineering Composite Material
摘要: 壳聚糖是天然多糖甲壳素脱除部分乙酰基后的产物,由于特殊的分子结构从而具有生物相容性、生物降解性、抗菌性等优良性质,因而被认为是具有更大潜力的功能性生物材料。随着对壳聚糖的进一步深入研究,近年来该材料已经逐渐发展到骨组织工程领域。本文将以壳聚糖的物理化学性质和生物学性质为基础,对骨组织工程中壳聚糖用于对复合骨组织支架的构成与制备作一综述,以期为该材料在骨组织工程中的应用研究提供参考。
Abstract: Chitosan is a natural polysaccharide produced by the partial removal of acetyl groups from chitin. Due to its special molecular structure and thus excellent properties such as biocompatibility, biodegradability and antibacterial properties, most studies have concluded that it has great potential as a functional biomaterial. With further in-depth research on chitosan, the material has been gradually developed into the field of bone tissue engineering in recent years. This paper will review the composition and preparation of chitosan for composite bone tissue scaffolds in bone tissue engineering based on the physicochemical and biological properties of chitosan, in order to provide a reference for the application of this material in bone tissue engineering.
文章引用:方佳瑶, 张帅, 何铮, 汪丽雯. 壳聚糖用于骨支架研究进展[J]. 临床医学进展, 2025, 15(4): 3500-3508. https://doi.org/10.12677/acm.2025.1541323

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