基于深度学习的乳腺癌多级诊断系统的设计与实现
Design and Implementation of Breast Cancer Multi Level Diagnosis System Based on Deep Learning
DOI: 10.12677/mos.2025.144363, PDF,   
作者: 郭晓杰, 章浩伟, 刘 颖*:上海理工大学健康科学与工程学院,上海;梁 浈:浙江深博医疗技术有限公司,浙江 嘉兴
关键词: 深度学习乳腺癌多级诊断微信小程序Deep Learning Breast Cancer Multi-Stage Diagnosis WeChat Mini Program
摘要: 乳腺癌是全球女性发病率最高的恶性肿瘤,传统筛查方法存在敏感性不足、依赖专业医师等问题。特别是对于偏远地区的女性而言,由于当地医疗资源条件、经济情况等因素的影响,从而对乳腺癌的预防和治疗存在一定的延后,很多患者因未能及时地治疗导致病情的恶化。本研究提出了一种基于深度学习的乳腺癌多级诊断系统,并通过对比ResNet50、VGGNeT、GoogleNet和CNN-ViT模型,最终选择准确率为93.47%,精确率为91.35%,召回率为91.50%,F1分数为91.56%的ResNet50模型作为本系统的诊断模型。将模型诊断结果与医生的实际经验相结合,最终得到一份相对准确的诊断报告。患者可在微信小程序及时地知道诊断结果,为下一步治疗提供便利性和快捷性。本系统为乳腺癌的预防和治疗提供了一种可行的方法。
Abstract: Breast cancer is the most prevalent malignant tumor among women globally. Traditional screening methods suffer from insufficient sensitivity and reliance on specialized physicians. Particularly for women in remote areas, factors such as limited medical resources, economic constraints, and geographical access delays prevention and treatment, leading to delayed interventions and disease progression for many patients. This study proposes a deep learning-based multi-stage breast cancer diagnosis system. By comparing ResNet50, VGGNeT, GoogleNet, and CNN-ViT models, we selected ResNet50 as the optimal model, achieving 93.47% accuracy, 91.35% precision, 91.50% recall, and an F1 score of 91.56%. The system integrates model predictions with clinical expertise to generate comprehensive diagnostic reports. Patients can receive real-time results via a WeChat Mini Program, facilitating prompt decision-making for subsequent treatment. This framework offers a feasible solution to improve breast cancer prevention and management, particularly in resource-limited settings.
文章引用:郭晓杰, 章浩伟, 梁浈, 刘颖. 基于深度学习的乳腺癌多级诊断系统的设计与实现[J]. 建模与仿真, 2025, 14(4): 1168-1179. https://doi.org/10.12677/mos.2025.144363

参考文献

[1] Sung, H., Ferlay, J., Siegel, R.L., Laversanne, M., Soerjomataram, I., Jemal, A., et al. (2021) Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 71, 209-249. [Google Scholar] [CrossRef] [PubMed]
[2] Park-Simon, T.W., Müller, V., Jackisch, C., et al. (2023) Arbeitsgemeinschaft Gynäkologische Onkologie Recommendations for the Diagnosis and Treatment of Patients with Early Breast Cancer: Update 2023. Breast Care (Basel), 18, 289-305.
[3] Bleyer, A. and Welch, H.G. (2012) Effect of Three Decades of Screening Mammography on Breast-Cancer Incidence. New England Journal of Medicine, 367, 1998-2005. [Google Scholar] [CrossRef] [PubMed]
[4] Dembrower, K., Wittenberg, T. and Lång, K. (2020) Artificial Intelligence in Breast Imaging: Potentials and Limitations. The Breast, 49, 44-48.
[5] Elmore, J.G. (2005) Screening for Breast Cancer. JAMA, 293, 1245-1256. [Google Scholar] [CrossRef] [PubMed]
[6] Kuhl, C.K. (2007) The Role of MRI in Breast Cancer Screening. Radiology, 244, 656-684.
[7] McKinney, S.M., Sieniek, M., Godbole, V., Godwin, J., Antropova, N., Ashrafian, H., et al. (2020) International Evaluation of an AI System for Breast Cancer Screening. Nature, 577, 89-94. [Google Scholar] [CrossRef] [PubMed]
[8] Pisano, E.D. and Yaffe, M.J. (2005) Digital Mammography: A Review of Technical Developments and Clinical Applications. Radiology, 234, 353-362. [Google Scholar] [CrossRef] [PubMed]
[9] Schnitt, S.J. (2010) Molecular Pathology of Breast Cancer: The Merging of Molecular and Traditional Pathology. The American Journal of Surgical Pathology, 34, e19-e24.
[10] Shen, D., Wu, G. and Suk, H. (2017) Deep Learning in Medical Image Analysis. Annual Review of Biomedical Engineering, 19, 221-248. [Google Scholar] [CrossRef] [PubMed]
[11] Smith, R.A., Andrews, K.S., Brooks, D., Fedewa, S.A., Manassaram‐Baptiste, D., Saslow, D., et al. (2019) Cancer Screening in the United States, 2019: A Review of Current American Cancer Society Guidelines and Current Issues in Cancer Screening. CA: A Cancer Journal for Clinicians, 69, 184-210. [Google Scholar] [CrossRef] [PubMed]
[12] Sood, R., Rositch, A.F., Shakoor, D., Ambinder, E., Pool, K., Pollack, E., et al. (2019) Ultrasound for Breast Cancer Detection Globally: A Systematic Review and Meta-Analysis. Journal of Global Oncology, 5, 1-17. [Google Scholar] [CrossRef] [PubMed]
[13] Yau, C. and Esserman, L. (2015) The Future of Breast Cancer Screening. The New England Journal of Medicine, 372, 2353-2358.
[14] Yedjou, C.G., Sims, J.N., Miele, L., Noubissi, F., Lowe, L., Fonseca, D.D., et al. (2019) Health and Racial Disparity in Breast Cancer. In: Ahmad, A., Ed., Breast Cancer Metastasis and Drug Resistance, Springer, 31-49. [Google Scholar] [CrossRef] [PubMed]
[15] Duffy, S.W., Tabár, L., Yen, A.M., Dean, P.B., Smith, R.A., Jonsson, H., et al. (2020) Mammography Screening Reduces Rates of Advanced and Fatal Breast Cancers: Results in 549,091 Women. Cancer, 126, 2971-2979. [Google Scholar] [CrossRef] [PubMed]
[16] Margolies, L.R., Rosenkrantz, A.B., Ayoola, A. and Khalil, H. (2016) Breast MRI for Cancer Detection and Characterization: A Review of Evidence-Based Clinical Applications. Academic Radiology, 23, 362-371.
[17] Román, M., Sala, M., Domingo, L. and Ascunce, N. (2017) Effect of False-Positives and Women’s Characteristics on Long-Term Adherence to Breast Cancer Screening: A Retrospective Cohort Study. BMC Cancer, 17, Article ID: 764.
[18] Teixeira, S.C., Leithner, D., Mayerhoefer, M.E., Martinez, D.F., Morris, E.A. and Jochelson, M.S. (2021) Imaging Algorithms for the Diagnosis, Staging, and Response Assessment of Breast Cancer: A Literature Review and Narrative Review of the Current Guidelines. Cancer Imaging, 21, 1-12.