Bertolotti综合征的治疗方法
Treatment Approaches for Bertolotti Syndrome
摘要: Bertolotti综合征指的是因腰骶移行椎横突单侧或双侧异常增大所导致的一系列症状与体征,患者常表现出腰骶部疼痛及下肢放射痛等,该病在临床上发病率较低,常被误诊。一般采用X线检查对Bertolotti综合征进行诊断,不过随着技术的进步,多层螺旋CT的多平面重建与容积再现技术在诊断Bertolotti综合征中展现出显著优势。对于Bertolotti综合征,传统的治疗手段如药物镇痛及局部阻滞等在实际应用中效果有限,现阶段手术治疗则涵盖肥大横突切除术、融合术及单侧双通道内镜下的神经根管减压术等,均具有较好的效果。不过部分手术创伤大、并发症多、复发率高,而椎间盘镜手术、单侧双通道内镜下神经根管减压术以及联合疗法成为治疗Bertolotti综合征的更优选择。
Abstract: Bertolotti syndrome refers to a series of symptoms and signs caused by unilateral or bilateral abnormal enlargement of the transverse processes of the lumbosacral transitional vertebra. Patients often present with lumbosacral pain and radiating pain in the lower limbs. The disease has a relatively low clinical incidence and is frequently misdiagnosed. X-ray examination is generally used for the diagnosis of Bertolotti syndrome. However, with technological advancements, multiplanar reconstruction and volume rendering techniques of multi-slice spiral CT have demonstrated significant advantages in diagnosing Bertolotti syndrome. For Bertolotti syndrome, traditional treatment methods such as pharmacological analgesia and local nerve blocks have limited efficacy in practical applications. At present, surgical treatments, including resection of the enlarged transverse process, fusion surgery, and unilateral biportal endoscopic nerve root canal decompression, have shown favorable outcomes. Nevertheless, some surgical procedures are associated with significant trauma, a high incidence of complications, and a high recurrence rate. Consequently, procedures such as microendoscopic discectomy, unilateral biportal endoscopic nerve root canal decompression, and combination therapies have emerged as superior options for treating Bertolotti syndrome.
文章引用:胡浩, 邓忠良. Bertolotti综合征的治疗方法[J]. 临床医学进展, 2025, 15(5): 440-445. https://doi.org/10.12677/acm.2025.1551391

参考文献

[1] 曹永泉, 唐少娜, 董云. 腰椎横突的影像学定位方法[J]. 解剖学研究, 2024, 46(5): 517-518.
[2] 林奕成, 陈哲, 张爱琪, 等. Bertolotti综合征的诊断与治疗研究进展[J]. 中华骨科杂志, 2024, 44(2): 119-125.
[3] Bari, S., Menon, V. and Bhuvanesh, S. (2025) Oral Pharmacological Management of Bertolotti Syndrome Presenting as Chronic Low Back Pain—A Case Report and Review of Literature. Journal of Orthopaedics, 62, 122-125. [Google Scholar] [CrossRef] [PubMed]
[4] 尹萌辰, 孙悦礼, 朱文浩, 等. Bertolotti综合征1例报告并文献复习[J]. 脊柱外科杂志, 2022, 20(1): 69-72.
[5] Carlos, A.J., Gabriela, D.M. and Isabella, L. (2025) Bertolotti Syndrome: Does It Really Exist? Systematic Review. Interdisciplinary Neurosurgery, 40, Article ID: 102008. [Google Scholar] [CrossRef
[6] 夏兰, 吴小三, 刘佳, 等. Bertolotti’s综合征致姿势步态异常1例[J]. 江苏医药, 2023, 49(7): 754-756.
[7] Jenkins, A.L., O’Donnell, J., Chung, R.J., Jenkins, S., Hawks, C., Lazarus, D., et al. (2023) Redefining the Classification for Bertolotti Syndrome: Anatomical Findings in Lumbosacral Transitional Vertebrae Guide Treatment Selection. World Neurosurgery, 175, e303-e313. [Google Scholar] [CrossRef] [PubMed]
[8] 王磊, 王琨, 裴昌军, 等. 多层螺旋CT多平面重建与容积再现技术在第5腰椎横突肥大综合征中的应用价值[J]. 实用医学影像杂志, 2016, 17(6): 471-474.
[9] Mikula, A.L., Lakomkin, N., Ransom, R.C., Flanigan, P.M., Waksdahl, L.A., Pennington, Z., et al. (2022) Operative Treatment of Bertolotti Syndrome: Resection versus Fusion. World Neurosurgery, 165, e311-e316. [Google Scholar] [CrossRef] [PubMed]
[10] McGrath, K., Schmidt, E., Rabah, N., Abubakr, M. and Steinmetz, M. (2021) Clinical Assessment and Management of Bertolotti Syndrome: A Review of the Literature. The Spine Journal, 21, 1286-1296. [Google Scholar] [CrossRef] [PubMed]
[11] 涂强, 丁焕文, 刘宝, 等. 第5腰椎横突肥大综合征的治疗策略[J]. 实用医学杂志, 2009, 25(19): 3257-3259.
[12] 杨智杰, 蓝海洋, 陈杰, 等. 第五腰椎横突肥大综合征的诊疗现状[J]. 中国当代医药, 2019, 26(29): 31-35.
[13] 李立钧, 杨明杰, 李昕, 等. 微创腰椎横突成形术治疗Bertolotti综合征[J]. 中国矫形外科杂志, 2009, 17(23): 1767-1769.
[14] 洪剑飞, 邱斌松, 毕擎, 等. 椎间盘镜手术治疗第五腰椎横突肥大综合征的前瞻性临床研究[J]. 全科医学临床与教育, 2019, 17(8): 704-706.
[15] 谢建荣, 王玉祥, 谢晓焜, 等. 手法配合臭氧治疗腰5横突肥大综合征33例[J]. 中医外治杂志, 2018, 27(1): 14-16.
[16] 董绍兴. BERTOLOTTI综合征诊疗策略[C]//中华医学会, 中华医学会疼痛学分会. 中华医学会疼痛学分会第十九届学术年会论文汇编. 玉溪: 玉溪市人民医院, 2023: 101.
[17] 黄勇兄, 程星, 余涛, 等. 远端综合征(FOS)的病因、诊断和治疗: 综述及个案报道[J]. 中国临床解剖学杂志, 2024, 42(6): 710-715.