术中预防性使用皮瓣转移乳头乳晕成形术在扩大切除联合整形手术治疗肉芽肿性小叶性乳腺炎中的临床效果观察

The Clinical Effect of Intraoperative Prophylactic Papillary Areolar Plasty with Flap Transfer in the Treatment of Granulomatous Lobular Mastitis by Extended Resection Combined with Plastic Surgery

摘要: 目的：探究肉芽肿性小叶性乳腺炎疾病干预中采用术中预防性使用皮瓣转移乳头乳晕成形术在扩大切除联合整形手术的价值。方法：根据随机数字表法将2023年6月~2024年6月收治的100例肉芽肿性小叶性乳腺炎患者，其中观察组实施术中预防性皮瓣转移乳头乳晕成形术于扩大切除联合整形手术治疗，对照组50例采用扩大切除联合整形手术治疗，对比两组生活质量、疼痛评分、炎症水平。结果：观察、对照组间干预前生活质量评分差异不明显(P > 0.05)，干预后生活质量评分更高(P < 0.05)，观察组更高(P < 0.05)；观察组术后2 h、4 h、12 h、24 h疼痛疼痛评分更低(P < 0.05)；干预前两组炎性因子水平差异不明显(P > 0.05)，干预后CRP、IL-6、TNF-α低于干预前(P < 0.05)，观察组更低(P < 0.05)；观察组治疗总有效率高于对照组(P < 0.05)。结论：在肉芽肿性小叶性乳腺炎疾病干预中采用术中预防性使用皮瓣转移乳头乳晕成形术在扩大切除联合整形手术较高，其能够改善患者生活质量，降低患者疼痛水平和炎症反应，提升治疗效果。

Abstract: Objective: To investigate the value of intraoperative prophylactic flap transfer papillary areolar plasty in the intervention of granulomatous lobular mastitis in the combination of extended resection and plastic surgery. How: A total of 100 patients with granulomatous lobular mastitis treated from June 2023 to June 2024 were selected by random number table method. The observation group underwent intraoperative prophylactic flap transfer papillareoplasty combined with extended resection and plastic surgery, while the control group received extended resection combined with plastic surgery for 50 cases. The quality of life, pain score and inflammation level were compared between the two groups. Results: There was no significant difference between the observation group and the control group before intervention (P > 0.05), but the score of life quality after intervention was higher (P < 0.05), and the score of life quality in the observation group was higher (P < 0.05). The pain scores of the observation group were lower at 2 h, 4 h, 12 h and 24 h after surgery (P < 0.05). The levels of inflammatory factors were not significantly different between the two groups before intervention (P > 0.05), CRP, IL-6 and TNF-α were lower after intervention than before intervention (P < 0.05), and the levels were lower in the observation group (P < 0.05). The total effective rate of observation group was higher than that of control group (P < 0.05). Conclusion: In the intervention of granulomatous lobular mastitis, intraoperative prophylactic papillary areolplasty with flap transfer is more effective than that of extended resection combined with plastic surgery, which can improve the quality of life of patients, reduce the level of pain and inflammatory response of patients, and enhance the therapeutic effect.