血必净结合乌司他丁在急诊脓毒血症患者临床治疗中的应用效果及TNF-α、IL-6水平影响分析

The Effect of Application of Xuebijing Combined with Ustekin in the Clinical Treatment of Emergency Sepsis Patients and the Influence of TNF-α and IL-6 Levels

摘要: 目的：分析血必净结合乌司他丁在急诊脓毒血症患者临床治疗中的应用效果及TNF-α、IL-6水平影响。方法：本次研究对象为2022年01月到2024年12月期间到我院接收的急诊脓毒血症患者，例数为60例，将所有患者应用随机数字表法进行分组，以对照组、观察组作为分组命名，两组患者的例数分别为30例、30例。对照组的患者实施常规治疗，观察组患者实施血必净结合乌司他丁治疗，观察两组治疗效果、炎症因子水平。结果：相较于对照组所纳入患者的治疗有效率，观察组更高，P < 0.05。相较于对照组所纳入患者的炎症因子水平，观察组更低，P < 0.05。相较于对照组所纳入患者的T细胞亚群，观察组更接近正常范围，P < 0.05。结论：针对急诊脓毒血症患者采取血必净结合乌司他丁治疗，能够有效降低炎症因子水平，很大程度上提高了治疗效果，值得应用和推广。

Abstract: Objective: To analyze the application effect of Xuebijing combined with Ustekin in the clinical treatment of emergency sepsis patients and the influence of TNF-α and IL-6 levels. Methods: The subjects of this study were emergency sepsis patients admitted to our hospital from January 2022 to December 2024, with a total of 60 cases. All patients were divided into groups using a random number table method, with the control group and the observation group as the group names, with 30 cases in each group. The patients in the control group were treated conventionally, and the patients in the observation group were treated with Xuebijing combined with Ustekin. The treatment effect and inflammation factor levels of the two groups were observed. Results: Compared with the treatment efficiency of the patients included in the control group, the observation group was higher, with P < 0.05. Compared with the levels of inflammatory factors in the patients included in the control group, those in the observation group were lower, with P < 0.05. Compared with the T cell subpopulations of the patients included in the control group, the observation group was closer to the normal range, with P < 0.05. Conclusion: For emergency sepsis patients, the application of Xuebijing combined with Ustekin can effectively reduce the level of factors, greatly improve the treatment effect, and is worth applying and popularizing.