三维重建术前规划在肝脏肿瘤微波消融术中的应用进展
The Application Progress of Preoperative Planning with Three-Dimensional Reconstruction in Microwave Ablation of Liver Tumors
摘要: 近年来随着计算机技术与医学影像学的迅速发展，三维重建技术在肿瘤治疗、骨科修复、器官移植、血管成形等医疗域领的应用也更加广泛，创新和精准成为其显著特征之一。该技术通过对二维影像数据进行处理与转化，从而生成三维模型，处理后的三维效果强化了体内的结构表达，提供了直观、量化的数据分析，医生根据生成的模型可从多个角度进行观察与规划。三维重建技术在微创手术、肿瘤治疗和个体化治疗等医疗领域中进展不一，图像精度、重建速度和成本控制都极大限制了其推广，受手术设备与操作熟练度等方面因素的影响，也制约了三维重建技术在医学中的应用。
Abstract: In recent years, driven by the rapid advancement of computer technology and medical imaging, three-dimensional reconstruction technology has been increasingly applied across various medical domains, including tumor treatment, orthopedic repair, organ transplantation, and angioplasty. Innovation and precision are among its most prominent characteristics. This technology generates three-dimensional models through the processing and transformation of two-dimensional image data. The resulting three-dimensional visualization enhances the representation of internal structures and facilitates intuitive and quantitative data analysis. Based on these reconstructed models, physicians can conduct multi-angle observations and develop comprehensive treatment plans. The development of three-dimensional reconstruction technology has significantly influenced minimally invasive surgery, tumor treatment, and personalized medicine. However, factors such as image accuracy, reconstruction speed, and cost-efficiency have posed substantial challenges to its widespread adoption. Additionally, the sophistication of surgical equipment and the proficiency of operators further constrain the practical application of this technology in clinical settings.
文章引用：王敏, 乔建梁. 三维重建术前规划在肝脏肿瘤微波消融术中的应用进展[J]. 临床医学进展, 2025, 15(5): 1446-1452. https://doi.org/10.12677/acm.2025.1551513

参考文献

[1] Pina, S., Ribeiro, V.P., Marques, C.F., Maia, F.R., Silva, T.H., Reis, R.L., et al. (2019) Scaffolding Strategies for Tissue Engineering and Regenerative Medicine Applications. Materials, 12, Article 1824. [Google Scholar] [CrossRef] [PubMed]
[2] Haleem, A. and Javaid, M. (2019) Polyether Ether Ketone (PEEK) and Its 3D Printed Implants Applications in Medical Field: An Overview. Clinical Epidemiology and Global Health, 7, 571-577. [Google Scholar] [CrossRef] 
[3] Ahangar, P., Cooke, M.E., Weber, M.H. and Rosenzweig, D.H. (2019) Current Biomedical Applications of 3D Printing and Additive Manufacturing. Applied Sciences, 9, Article 1713. [Google Scholar] [CrossRef] 
[4] Yan, Q., Dong, H., Su, J., Han, J., Song, B., Wei, Q., et al. (2018) A Review of 3D Printing Technology for Medical Applications. Engineering, 4, 729-742. [Google Scholar] [CrossRef] 
[5] Kim, G.B., Lee, S., Kim, H., Yang, D.H., Kim, Y., Kyung, Y.S., et al. (2016) Three-Dimensional Printing: Basic Principles and Applications in Medicine and Radiology. Korean Journal of Radiology, 17, 182-197. [Google Scholar] [CrossRef] [PubMed]
[6] Haleem, A. and Javaid, M. (2019) 3D Scanning Applications in Medical Field: A Literature-Based Review. Clinical Epidemiology and Global Health, 7, 199-210. [Google Scholar] [CrossRef] 
[7] Shafiee, A. and Atala, A. (2016) Printing Technologies for Medical Applications. Trends in Molecular Medicine, 22, 254-265. [Google Scholar] [CrossRef] [PubMed]
[8] Marro, A., Bandukwala, T. and Mak, W. (2016) Three-Dimensional Printing and Medical Imaging: A Review of the Methods and Applications. Current Problems in Diagnostic Radiology, 45, 2-9. [Google Scholar] [CrossRef] [PubMed]
[9] Ruiter, S.J.S., Heerink, W.J. and de Jong, K.P. (2019) Liver Microwave Ablation: A Systematic Review of Various FDA-Approved Systems. European Radiology, 29, 4026-4035. [Google Scholar] [CrossRef] [PubMed]
[10] Ruiter, S.J.S., Heerink, W.J. and de Jong, K.P. (2019) Microwave Ablation Compared with Radiofrequency Ablation for the Treatment of Liver Cancer: A Systematic Review and Meta-Analysis. Radiology and Oncology, 55, 145-154.
[11] Poggi, G. (2015) Microwave Ablation of Hepatocellular Carcinoma. World Journal of Hepatology, 7, 2578-2589. [Google Scholar] [CrossRef] [PubMed]
[12] Mocan, T., Nenu, I., Radu, P., et al. (2020) Microwave Ablation in the Treatment of Liver Tumors. Medical Ultrasound, 22, 85-90.
[13] Violi, N.V., Duran, R., Guiu, B., et al. (2018) Efficacy of Microwave Ablation versus Radiofrequency Ablation for the Treatment of Hepatocellular Carcinoma. The Lancet Gastroenterology & Hepatology, 3, 329-338.
[14] Dou, J., Liang, P. and Yu, J. (2016) Microwave Ablation for Liver Tumors. Abdominal Radiology, 41, 650-658. [Google Scholar] [CrossRef] [PubMed]
[15] Vogl, T., Nour-Eldin, N., Hammerstingl, R., Panahi, B. and Naguib, N. (2017) Microwave Ablation (MWA): Basics, Technique and Results in Primary and Metastatic Liver Neoplasms—Review Article. RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 189, 1055-1066. [Google Scholar] [CrossRef] [PubMed]
[16] Ghosh, S., Clymer, J.W., Glassberg, M.B., et al. (2019) Microwave Ablation Compared with Radiofrequency Ablation for the Treatment of Hepatocellular Carcinoma and Liver Metastases. Journal of Cancer Therapy, 7, 381-388.
[17] Sindram, D., Simo, K.A., Swan, R.Z., Razzaque, S., Niemeyer, D.J., Seshadri, R.M., et al. (2015) Laparoscopic Microwave Ablation of Human Liver Tumours Using a Novel Three-Dimensional Magnetic Guidance System. HPB, 17, 87-93. [Google Scholar] [CrossRef] [PubMed]
[18] Iannitti, D., Sastry, A., Swet, J., Baker, E., Martinie, J., Vrochides, D., et al. (2017) A Novel 3-Dimensional Electromagnetic Guidance System Increases Accuracy of Microwave Antenna Placement. HPB, 19, S53-S54. [Google Scholar] [CrossRef] 
[19] Muglia, R., Marra, P., Pinelli, D., Dulcetta, L., Carbone, F.S., Barbaro, A., et al. (2023) Technical and Clinical Outcomes of Laparoscopic-Laparotomic Hepatocellular Carcinoma Thermal Ablation with Microwave Technology: Case Series and Review of Literature. Cancers, 16, Article 92. [Google Scholar] [CrossRef] [PubMed]
[20] Sastry, A.V., Swet, J.H., et al. (2015) Laparoscopic Ablation Therapies for Hepatocellular Carcinoma: Could Specific Indications for the Laparoscopic Approach Influence the Effectiveness? Surgical Oncology, 21, 261-270.
[21] Swet, J.H., Sastry, A.V., et al. (2016) Laparoscopic Microwave Ablation of Liver Tumors: An Effective Alternative to Resection. Surgical Oncology, 21, 324-331.
[22] Collins, J.A., Heiselman, J.S., et al. (2019) Laparoscopic Image-Based Navigation for Microwave Ablation of Liver Tumors—A Multi-Center Study. Journal of Medical Imaging, 6, Article 025007.
[23] Thomas, M., Dieplinger, G., Datta, R., Kleinert, R., Fuchs, H., Bunck, A., et al. (2020) Navigated Laparoscopic Microwave Ablation of Tumour Mimics in Pig Livers—A Randomized Ex-Vivo Trial. Zeitschrift für Gastroenterologie, 58, e203. [Google Scholar] [CrossRef] 
[24] Liu, F., Cheng, Z., Han, Z., Yu, X., Yu, M. and Liang, P. (2017) A Three-Dimensional Visualization Preoperative Treatment Planning System for Microwave Ablation in Liver Cancer: A Simulated Experimental Study. Abdominal Radiology, 42, 1788-1793. [Google Scholar] [CrossRef] [PubMed]
[25] Yang, J., Li, X., Yu, J., et al. (2020) 3D Visualization Operative Planning System and Ultrasound-Guided Percutaneous Microwave Ablation for Hepatocellular Carcinoma: A Clinical Study. BMC Cancer, 20, Article 518.
[26] Li, H., Yi, T. and Wu, Z. (2008) Suspension Culture Combined with Chemotherapeutic Agents for Sorting of Breast Cancer Stem Cells. BMC Cancer, 8, Article No. 135. [Google Scholar] [CrossRef] [PubMed]
[27] Wu, S., Li, X., Yu, X., et al. (2019) Ultrasound-Guided Percutaneous Microwave Ablation Assisted by a Three-Dimensional Visualization Preoperative Treatment Planning System for Larger Adrenal Tumors. Journal of Cancer Therapy, 10, 491-501.
[28] Zhang, Y., Wang, M., Wang, L., Zhang, S., Sun, H. and Liu, J. (2023) Preliminary Study of 3D Printing Technology for Extracorporeal Positioning Guide Assisted Ultrasound-Guided Microwave Ablation of the Liver. Expert Review of Medical Devices, 20, 1227-1233. [Google Scholar] [CrossRef] [PubMed]
[29] Qi, E., Zhang, S., Li, X., et al. (2022) Comparison of Percutaneous Microwave Ablation and Surgical Resection for Hepatocellular Carcinoma in the Caudate Lobe. Journal of Cancer Research and Clinical Oncology, 148, 1283-1292.
[30] Zhang, D., Wu, W. and Liang, P. (2015) Three-Dimensional Visualization Technology and Therapy Planning System for Microwave Ablation Therapy of Liver Tumor. Microwave Ablation Treatment of Solid Tumors, 342-356.
[31] Heshmat, A., O’Connor, C.S., Albuquerque Marques Silva, J., Paolucci, I., Jones, A.K., Odisio, B.C., et al. (2024) Using Patient-Specific 3D Modeling and Simulations to Optimize Microwave Ablation Therapy for Liver Cancer. Cancers, 16, Article 2095. [Google Scholar] [CrossRef] [PubMed]
[32] Sánchez-Margallo, J.A., Plaza de Miguel, C., Fernández Anzules, R.A. and Sánchez-Margallo, F.M. (2021) Application of Mixed Reality in Medical Training and Surgical Planning Focused on Minimally Invasive Surgery. Frontiers in Virtual Reality, 2, Article 692641. [Google Scholar] [CrossRef] 
[33] Pierzchajlo, N., Stevenson, T.C., Huynh, H., Nguyen, J., Boatright, S., Arya, P., et al. (2023) In Reply to the Letter to the Editor Regarding “augmented Reality in Minimally Invasive Spinal Surgery: A Narrative Review of Available Technology”. World Neurosurgery, 180, Article 261. [Google Scholar] [CrossRef] [PubMed]
[34] Momin, A.A., Steinmetz, M.P., Eltorai, A., et al. (2020) Evolution of Minimally Invasive Lumbar Spine Surgery. World Neurosurgery, 141, 118-124.
[35] Marescaux, J. and Diana, M. (2015) Next Step in Minimally Invasive Surgery: Hybrid Image-Guided Surgery. Journal of Pediatric Surgery, 50, 30-36. [Google Scholar] [CrossRef] [PubMed]
[36] Wu, Z., Xing, W., Wu, X., et al. (2017) Application and Prospect of Mixed Reality Technology in the Medical Field. Medical & Biological Engineering & Computing, 56, 783-796.
[37] Porpiglia, F., Checcucci, E., Amparore, D., Peretti, D., Piramide, F., De Cillis, S., et al. (2022) Percutaneous Kidney Puncture with Three-Dimensional Mixed-Reality Hologram Guidance: From Preoperative Planning to Intraoperative Navigation. European Urology, 81, 588-597. [Google Scholar] [CrossRef] [PubMed]
[38] Ye, Z., Hu, H., Shao, Z., et al. (2019) A Combination of Three-Dimensional Printing and Computer-Assisted Virtual Surgical Procedure for Preoperative Planning of Acetabular Fracture Reduction. Injury, 51, 762-769.
[39] Tonutti, M., Elson, D.S., Yang, G., Darzi, A.W. and Sodergren, M.H. (2017) The Role of Technology in Minimally Invasive Surgery: State of the Art, Recent Developments and Future Directions. Postgraduate Medical Journal, 93, 159-167. [Google Scholar] [CrossRef] [PubMed]

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