肾综合征出血热患者应用股静脉置管气压治疗的效果研究

Study on the Effect of Femoral Vein Catheterization in the Treatment of Hemorrhagic Fever with Renal Syndrome

摘要: 目的：肾综合征出血热(HFRS)是一种由汉坦病毒引起的急性传染病，表现为发热、出血和肾功能衰竭。本研究探讨股静脉置管与气压治疗在HFRS患者中的临床疗效和安全性。方法：本研究选取2017年至2020年之间入住我院感染科病房的239肾综合征出血热股静脉管患者，使用随机数字表法将患者分为新型治疗组和传统方法组，比较分析两组患者的治疗效果。结果：新型治疗组患者的血栓形成率低于对照组(P < 0.05)。影响血栓形成的因素包括性别、置管时间等。结论：股静脉置管气压治疗能够有效应用于HFRS患者，预防并缓解股静脉血栓形成，年龄不会影响血栓发生风险，但男性性别和置管时间越长会增加血栓风险，同时在置管侧肢体处进行气压治疗也可能增加血栓发生的概率，APTT越长，血栓发生率越低，但出血和感染风险有所增加。

Abstract: Objective: Hemorrhagic fever with renal syndrome (HFRS) is an acute infectious disease caused by Hantavirus. It is characterized by fever, hemorrhage and renal failure. This study investigated the clinical efficacy and safety of femoral vein catheterization and barometric therapy in patients with HFRS. Methods: In this study, 239 patients with hemorrhagic fever with renal syndrome who were admitted to the infection ward of our hospital from 2017 to 2020 were selected and divided into the novel treatment group and the traditional treatment group using random number table method, and the therapeutic effects of the two groups were compared and analyzed. Results: The rate of thrombosis in the new treatment group was lower than that in the control group (P < 0.05). The factors influencing thrombus formation include gender and catheterization time. Conclusion: Femoral vein catheterization pneumatic therapy can be effectively applied in HFRS patients to prevent and alleviate femoral vein thrombosis. Age does not affect the risk of thrombosis, but male gender and longer catheterization time will increase the risk of thrombosis. Meanwhile, pneumatic therapy in the limbs on the side of catheterization may also increase the probability of thrombosis. But there is an increased risk of bleeding and infection.