镇痛中药的研究进展
Research Progress of Analgesic Chinese Medicine
DOI: 10.12677/pi.2025.143019, PDF,   
作者: 周春燕, 张梦焦, 李 霁*：昆明医科大学药学院暨云南省天然药物药理重点实验室，云南 昆明；云南省现代生物医药产业学院，云南 昆明；刘 勤：云南省食品药品监督检验研究院生物制品检定所，云南 昆明；刘玉苹*：昆明医科大学药学院暨云南省天然药物药理重点实验室，云南 昆明
关键词: 镇痛；中药；活性成分；应用领域；药学研究；Analgesic； Traditional Chinese Medicine； Active Ingredient； Application Field； Pharmaceutical Research
摘要: 疼痛是医学领域重点关注问题，WHO推荐的西医药物缓解疼痛存在局限性，开发新型镇痛药物成为重要方向。中医药在疼痛治疗中不良反应少，长期使用安全性高，日益受到关注。中药活性成分包括生物碱类、黄酮类、皂苷类和香豆素等，具有多靶点作用特点。镇痛中药广泛应用于神经性疼痛的系统调控、偏头痛的递质网络调节、原发性痛经的多维度干预等领域。本文从上述两方面以及药学研究方面(物质基础、质量控制、药效作用及药物代谢动力学)进行阐述，为开发新型镇痛药物提供参考。
Abstract: Pain is a key issue in the medical field. The western medicine recommended by the WHO for pain relief has limitations. Developing new analgesic drugs has become an important direction. Traditional Chinese medicine which has fewer adverse reactions in pain treatment and high safety for long-term use is increasingly attracting attention. The analgesic active ingredients of traditional Chinese medicine include alkaloids, flavonoids, saponins, coumarins, and so on. They have the characteristics of multi-target action. In addition, this analgesic Chinese medicine is widely used in the systematic regulation of neuropathic pain, the regulation of neurotransmitter networks in migraines, and multi-dimensional intervention in primary dysmenorrhea, etc. This article elaborates on the above two aspects and the pharmaceutical research aspects (material basis, quality control, pharmacological effects, and pharmacokinetics), in order to provide a reference for the development of new analgesic drugs.
文章引用：周春燕, 刘勤, 张梦焦, 刘玉苹, 李霁. 镇痛中药的研究进展[J]. 药物资讯, 2025, 14(3): 154-161. https://doi.org/10.12677/pi.2025.143019

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