孙远征教授“形神同调”针刺治疗围绝经期抑郁的临床经验

Professor Sun Yuanzheng’s Clinical Experience in Treating Perimenopausal Depression with Acupuncture under the Guidance of the Theory of Brain-Intestinal Axis: “The Form and Spirit Are in Harmony”

摘要: 围绝经期抑郁(perimenopausal depression, PMD)是指绝经前后因内分泌波动而引起的严重情绪障碍，显著影响女性生活质量。其病理机制复杂多样，以肠道菌群改变作为影响抑郁发病的重要框架之一。孙远征教授从中医学整体观念出发认为围绝经期抑郁属于形神共病，以“神志失调”“脏腑虚损”为关键病机，因此将形神失调与脑肠轴理论相结合，通过“形神同调”的针刺疗法调节神经–内分泌–免疫网络从而改善围绝经期抑郁症状具有较好的临床疗效。本文总结孙远征在脑肠轴理论指导下对围绝经期抑郁形神共病的认识与诊疗经验，以期对该病临床诊疗提供新思路。

Abstract: Perimenopausal depression (PMD) is a serious mood disorder caused by endocrine fluctuations before and after menopause, which significantly affects women’s quality of life. Its pathologic mechanisms are complex and varied, with changes in intestinal flora as one of the important frameworks affecting the pathogenesis of depression. Prof. Sun Yuanzheng believes that perimenopausal depression belongs to form-spirit co-morbidity from the holistic concept of Chinese medicine, with “disorders of spirit and mind” and “deficiencies of the five viscera” as the key pathogenesis, and therefore combines form-spirit disorders and the theory of the brain-intestinal axis through the “form-spirit co-modulation” method. Therefore, combining the theory of “form and spirit disorder” with the theory of brain-intestine axis, and regulating the neuro-endocrine-immune network through the acupuncture therapy of “The form and spirit are in harmony” has better clinical efficacy in improving the symptoms of perimenopausal depression. This article summarizes Sun Yuanzheng’s understanding of perimenopausal depression and his experience in diagnosis and treatment under the guidance of the brain-gut axis theory, with a view to providing new ideas for the clinical diagnosis and treatment of this disease.