品行障碍共情缺陷的认知神经机制的研究现状与展望
Present Progress and Perspectives on the Neurocognitive Mechanism of Juvenile Empathy Deficit in Conduct Disorders
DOI: 10.12677/ap.2025.156378, PDF,    科研立项经费支持
作者: 李佳洛, 甘 琴, 郑成卓, 胡友军, 张积标*：江汉大学教育学院心理学系，湖北 武汉
关键词: 品行障碍；共情缺陷；认知神经机制；脑成像；Conduct Disorder； Empathy Deficit； Neurocognitive Mechanisms； Neuroimaging
摘要: 品行障碍(Conduct Disorder, CD)是儿童青少年期最常见的精神心理障碍之一，具有预后性差、破坏性大和社会负担重的特点，是影响社会稳定的一大重要因素。在过去20年的研究中，研究者已充分肯定了共情能力在不同亚型品行障碍及反社会行为的发生和发展过程中的重要作用。本文主要以品行障碍共情缺陷(冷酷无情特质)为切入点探讨其认知神经机制，为其精确诊断和有效干预提供客观的神经生物学依据。
Abstract: Conduct disorder (CD) is one of the most common mental disorders in children and adolescents, which is characterized by poor prognosis, great destructiveness and heavy social burden, as well as a major influence factor of social instability. In the past 20 years, investigators have fully confirmed the important role of empathy in the formation of different conduct disorders and the occurrence and development of antisocial behavior. This present paper mainly focused on the neurocognitive mechanisms of empathy deficit (callous unemotional trait) in CD individuals, in order to provide objective neurobiological basis for accurate diagnosis and effective intervention of CD.
文章引用：李佳洛, 甘琴, 郑成卓, 胡友军, 张积标 (2025). 品行障碍共情缺陷的认知神经机制的研究现状与展望. 心理学进展, 15(6), 305-312. https://doi.org/10.12677/ap.2025.156378

参考文献

[1] 陈慧, 何婷, 唐远琼, 唐怡欣, 陆风勇, 蔺秀云(2021). 共情与青少年内外化问题的关系及影响机制. 心理发展与教育, 37(3), 439-446.
[2] 欧阳谢璐(2021). 与青春期学生共情式沟通的个案探究. 现代基础教育研究, 44(4), 167-169.
[3] 颜志强, 苏彦捷(2021). 认知共情和情绪共情的发展差异: 元分析初探. 心理发展与教育, 37(1), 1-9.
[4] 张积标, 金鸣, 魏强, 等(2019). 反社会行为人群大脑灰质结构改变的Meta分析. 中国临床心理学杂志, 27(5), 863-868.
[5] 张积标, 周晨晖, 金鸣, 等(2021). 反社会行为人群白质微结构异常: 一项基于体素的元分析. 中国临床心理学杂志, 29(6), 1139-1144.
[6] Aggensteiner, P., Holz, N. E., Böttinger, B. W., Baumeister, S., Hohmann, S., Werhahn, J. E. et al. (2022). The Effects of Callous-Unemotional Traits and Aggression Subtypes on Amygdala Activity in Response to Negative Faces. Psychological Medicine, 52, 476-484.[CrossRef] [PubMed]
[7] Airdrie, J. N., Langley, K., Thapar, A., & van Goozen, S. H. M. (2018). Facial Emotion Recognition and Eye Gaze in Attention-Deficit/Hyperactivity Disorder with and without Comorbid Conduct Disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 57, 561-570.[CrossRef] [PubMed]
[8] APA (2013). Diagnostic and Statistical Manual of Mental Disorders (5th ed.). American Psychiatric Publishing.
[9] Arioli, M., Cattaneo, Z., Ricciardi, E., & Canessa, N. (2021). Overlapping and Specific Neural Correlates for Empathizing, Affective Mentalizing, and Cognitive Mentalizing: A Coordinate‐Based Meta‐Analytic Study. Human Brain Mapping, 42, 4777-4804.[CrossRef] [PubMed]
[10] Ayano, G., Abraha, M., Tsegay, L., & Gizachew, Y. (2024). Umbrella Review of the Global Prevalence of Conduct Disorder in Children and Adolescents. Psychiatric Quarterly, 95, 173-183.[CrossRef] [PubMed]
[11] Billeci, L., Muratori, P., Calderoni, S., Chericoni, N., Levantini, V., Milone, A. et al. (2019). Emotional Processing Deficits in Italian Children with Disruptive Behavior Disorder: The Role of Callous Unemotional Traits. Behaviour Research and Therapy, 113, 32-38.[CrossRef] [PubMed]
[12] Blair, R. J. R., Leibenluft, E., & Pine, D. S. (2014). Conduct Disorder and Callous-Unemotional Traits in Youth. New England Journal of Medicine, 371, 2207-2216.[CrossRef] [PubMed]
[13] Bloom, P. (2017). Empathy and Its Discontents. Trends in Cognitive Sciences, 21, 24-31.[CrossRef] [PubMed]
[14] Coll, M., Viding, E., Rütgen, M., Silani, G., Lamm, C., Catmur, C. et al. (2017). Are We Really Measuring Empathy? Proposal for a New Measurement Framework. Neuroscience & Biobehavioral Reviews, 83, 132-139.[CrossRef] [PubMed]
[15] Dadds, M. R., Allen, J. L., Oliver, B. R., Faulkner, N., Legge, K., Moul, C. et al. (2012a). Love, Eye Contact and the Developmental Origins of Empathy v. Psychopathy. British Journal of Psychiatry, 200, 191-196.[CrossRef] [PubMed]
[16] Dadds, M. R., Cauchi, A. J., Wimalaweera, S., Hawes, D. J., & Brennan, J. (2012b). Outcomes, Moderators, and Mediators of Empathic-Emotion Recognition Training for Complex Conduct Problems in Childhood. Psychiatry Research, 199, 201-207.[CrossRef] [PubMed]
[17] Dadds, M. R., El Masry, Y., Wimalaweera, S., & Guastella, A. J. (2008). Reduced Eye Gaze Explains “Fear Blindness” in Childhood Psychopathic Traits. Journal of the American Academy of Child & Adolescent Psychiatry, 47, 455-463.[CrossRef] [PubMed]
[18] De Brito, S. A., McCrory, E. J., Mechelli, A., Wilke, M., Jones, A. P., Hodgins, S. et al. (2011). Small, but Not Perfectly Formed: Decreased White Matter Concentration in Boys with Psychopathic Tendencies. Molecular Psychiatry, 16, 476-477.[CrossRef] [PubMed]
[19] De Brito, S. A., Mechelli, A., Wilke, M., Laurens, K. R., Jones, A. P., Barker, G. J. et al. (2009). Size Matters: Increased Grey Matter in Boys with Conduct Problems and Callous-Unemotional Traits. Brain, 132, 843-852.[CrossRef] [PubMed]
[20] Decety, J., Chen, C., Harenski, C., & Kiehl, K. A. (2013). An fMRI Study of Affective Perspective Taking in Individuals with Psychopathy: Imagining Another in Pain Does Not Evoke Empathy. Frontiers in Human Neuroscience, 7, Article No. 489.[CrossRef] [PubMed]
[21] Dryburgh, N. S. J., & Vachon, D. D. (2019). Relating Sex Differences in Aggression to Three Forms of Empathy. Personality and Individual Differences, 151, Article ID: 109526.[CrossRef] 
[22] Elowsky, J., Bajaj, S., Bashford-Largo, J., Zhang, R., Mathur, A., Schwartz, A. et al. (2022). Differential Associations of Conduct Disorder, Callous-Unemotional Traits and Irritability with Outcome Expectations and Values Regarding the Consequences of Aggression. Child and Adolescent Psychiatry and Mental Health, 16, Article No. 38.[CrossRef] [PubMed]
[23] Elster, E. M., Pauli, R., Baumann, S., De Brito, S. A., Fairchild, G., Freitag, C. M. et al. (2024). Impaired Punishment Learning in Conduct Disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 63, 454-463.[CrossRef] [PubMed]
[24] Frick, P. J., & Kemp, E. C. (2021). Conduct Disorders and Empathy Development. Annual Review of Clinical Psychology, 17, 391-416.[CrossRef] [PubMed]
[25] Fu, W., Wang, C., Chai, H., & Xue, R. (2022). Examining the Relationship of Empathy, Social Support, and Prosocial Behavior of Adolescents in China: A Structural Equation Modeling Approach. Humanities and Social Sciences Communications, 9, Article No. 269.[CrossRef] 
[26] Gao, Y., Staginnus, M., Gao, Y., Staginnus, M., Townend, S., Arango, C. et al. (2024). Cortical Structure and Subcortical Volumes in Conduct Disorder: A Coordinated Analysis of 15 International Cohorts from the Enigma-Antisocial Behavior Working Group. The Lancet Psychiatry, 11, 620-632.[CrossRef] [PubMed]
[27] Jiang, Y., Gao, Y., Dong, D., Sun, X., Situ, W., & Yao, S. (2023). Structural Abnormalities in Adolescents with Conduct Disorder and High versus Low Callous Unemotional Traits. European Child & Adolescent Psychiatry, 32, 193-203.[CrossRef] [PubMed]
[28] Jones, A. P., Happé, F. G. E., Gilbert, F., Burnett, S., & Viding, E. (2010). Feeling, Caring, Knowing: Different Types of Empathy Deficit in Boys with Psychopathic Tendencies and Autism Spectrum Disorder. Journal of Child Psychology and Psychiatry, 51, 1188-1197.[CrossRef] [PubMed]
[29] Lockwood, P. L., Sebastian, C. L., McCrory, E. J., Hyde, Z. H., Gu, X., De Brito, S. A. et al. (2013). Association of Callous Traits with Reduced Neural Response to Others’ Pain in Children with Conduct Problems. Current Biology, 23, 901-905.[CrossRef] [PubMed]
[30] Mackes, N. K., Golm, D., O’Daly, O. G., Sarkar, S., Sonuga-Barke, E. J. S., Fairchild, G. et al. (2018). Tracking Emotions in the Brain—Revisiting the Empathic Accuracy Task. NeuroImage, 178, 677-686.[CrossRef] [PubMed]
[31] Marsh, A. A. (2018). The Neuroscience of Empathy. Current Opinion in Behavioral Sciences, 19, 110-115.[CrossRef] 
[32] Martin‐Key, N. A., Graf, E. W., Adams, W. J., & Fairchild, G. (2018). Facial Emotion Recognition and Eye Movement Behaviour in Conduct Disorder. Journal of Child Psychology and Psychiatry, 59, 247-257.[CrossRef] [PubMed]
[33] Moul, C., Hawes, D. J., & Dadds, M. R. (2018). Mapping the Developmental Pathways of Child Conduct Problems through the Neurobiology of Empathy. Neuroscience & Biobehavioral Reviews, 91, 34-50.[CrossRef] [PubMed]
[34] Pauli, R., Kohls, G., Tino, P., Rogers, J. C., Baumann, S., Ackermann, K. et al. (2023). Machine Learning Classification of Conduct Disorder with High versus Low Levels of Callous-Unemotional Traits Based on Facial Emotion Recognition Abilities. European Child & Adolescent Psychiatry, 32, 589-600.[CrossRef] [PubMed]
[35] Preston, S. D., Ermler, M., Lei, Y., & Bickel, L. (2020). Understanding Empathy and Its Disorders through a Focus on the Neural Mechanism. Cortex, 127, 347-370.[CrossRef] [PubMed]
[36] Sebastian, C. L., Fontaine, N. M. G., Bird, G., Blakemore, S., De Brito, S. A., McCrory, E. J. P. et al. (2012). Neural Processing Associated with Cognitive and Affective Theory of Mind in Adolescents and Adults. Social Cognitive and Affective Neuroscience, 7, 53-63.[CrossRef] [PubMed]
[37] Sundram, F., Deeley, Q., Sarkar, S., Daly, E., Latham, R., Craig, M. et al. (2012). White Matter Microstructural Abnormalities in the Frontal Lobe of Adults with Antisocial Personality Disorder. Cortex, 48, 216-229.[CrossRef] [PubMed]
[38] Sylvers, P. D., Brennan, P. A., & Lilienfeld, S. O. (2011). Psychopathic Traits and Pre-Attentive Threat Processing in Children: A Novel Test of the Fearlessness Hypothesis. Psychological Science, 22, 1280-1287.[CrossRef] [PubMed]
[39] Taber-Thomas, B. C., Asp, E. W., Koenigs, M., Sutterer, M., Anderson, S. W., & Tranel, D. (2014). Arrested Development: Early Prefrontal Lesions Impair the Maturation of Moral Judgement. Brain, 137, 1254-1261.[CrossRef] [PubMed]
[40] Tesli, N., Jaholkowski, P., Haukvik, U. K., Jangmo, A., Haram, M., Rokicki, J. et al. (2024). Conduct Disorder—A Comprehensive Exploration of Comorbidity Patterns, Genetic and Environmental Risk Factors. Psychiatry Research, 331, Article ID: 115628.[CrossRef] [PubMed]
[41] Tillem, S., Conley, M. I., & Baskin-Sommers, A. (2022). Conduct Disorder Symptomatology Is Associated with an Altered Functional Connectome in a Large National Youth Sample. Development and Psychopathology, 34, 1573-1584.[CrossRef] [PubMed]
[42] Tkalcec, A., Bierlein, M., Seeger‐Schneider, G., Walitza, S., Jenny, B., Menks, W. M. et al. (2023). Empathy Deficits, Callous‐unemotional Traits and Structural Underpinnings in Autism Spectrum Disorder and Conduct Disorder Youth. Autism Research, 16, 1946-1962.[CrossRef] [PubMed]
[43] Viding, E., & McCrory, E. (2015). Developmental Risk for Psychopathy. In A. Thapar, et al. (Eds.), Rutter’s Child and Adolescent Psychiatry (6th ed., pp. 966-980). John Wiley & Sons, Ltd.
[44] Viding, E., & McCrory, E. (2020). Disruptive Behavior Disorders: The Challenge of Delineating Mechanisms in the Face of Heterogeneity. American Journal of Psychiatry, 177, 811-817.[CrossRef] [PubMed]
[45] Viding, E., Sebastian, C. L., Dadds, M. R., Lockwood, P. L., Cecil, C. A. M., De Brito, S. A. et al. (2012). Amygdala Response to Preattentive Masked Fear in Children with Conduct Problems: The Role of Callous-Unemotional Traits. American Journal of Psychiatry, 169, 1109-1116.[CrossRef] [PubMed]
[46] Waller, R., Hawes, S. W., Byrd, A. L., Dick, A. S., Sutherland, M. T., Riedel, M. C. et al. (2020). Disruptive Behavior Problems, Callous-Unemotional Traits, and Regional Gray Matter Volume in the Adolescent Brain and Cognitive Development Study. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 5, 481-489.[CrossRef] [PubMed]
[47] Zaki, J., & Ochsner, K. N. (2012). The Neuroscience of Empathy: Progress, Pitfalls and Promise. Nature Neuroscience, 15, 675-680.[CrossRef] [PubMed]
[48] Zhang, J., Zhu, X., Wang, X., Gao, J., Shi, H., Huang, B. et al. (2014). Increased Structural Connectivity in Corpus Callosum in Adolescent Males with Conduct Disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 53, 466-475.e1.[CrossRef] [PubMed]