张朝晖教授基于气血阴阳论治血管腔内疾病的经验
Professor Zhaohui Zhang’s Experience in Treating Intravascular Diseases Based on Qi, Blood, Yin and Yang Theory
DOI: 10.12677/tcm.2025.147419, PDF,    科研立项经费支持
作者: 陈 肯:天津中医药大学研究生院,天津;天津中医药大学中医疮疡研究所,天津;张朝晖*:天津中医药大学中医疮疡研究所,天津;天津中医药大学第二附属医院中医外科,天津
关键词: 血管腔内疾病名医经验张朝晖Intravascular Disease Experience of Famous Doctors Zhaohui Zhang
摘要: 血管腔内疾病是冠心病、外周动脉疾病等的主要病理基础。天津市名中医张朝晖教授认为,人体气血阴阳与血管腔内疾病的病因病机及临床表现之间存在联系,强调治疗须在现代医学精准干预局部病变的基础上,从整体出发调节气血阴阳、脏腑功能,运用益气活血、化痰祛湿、寒热兼调等方法,协同增效,临床疗效显著。附验案一则以佐证。
Abstract: Intravascular diseases are the main pathological basis of coronary heart disease, peripheral arterial disease, etc. Professor Zhaohui Zhang, a famous traditional Chinese medicine doctor in Tianjin, believes that there is a connection between the human qi, blood, yin and yang and the etiology, pathogenesis and clinical manifestations of intravascular diseases. He emphasized that treatment must be based on the precise intervention of local lesions in modern medicine, and regulate the functions of qi, blood, yin and yang, and internal organs from the overall perspective. He uses methods such as invigorating qi and promoting blood circulation, relieving phlegm and removing dampness, and regulating cold and heat. It synergistically enhances efficacy and has significant clinical efficacy. A case is attached to support it.
文章引用:陈肯, 张朝晖. 张朝晖教授基于气血阴阳论治血管腔内疾病的经验[J]. 中医学, 2025, 14(7): 2859-2865. https://doi.org/10.12677/tcm.2025.147419

参考文献

[1] 国家心血管病中心, 中国心血管健康与疾病报告编写组, 胡盛寿. 中国心血管健康与疾病报告2023概要[J]. 中国循环杂志, 2024, 39(7): 625-660.
[2] 魏立春, 谷涌泉, 郭连瑞, 等. 下肢动脉腔内载药治疗的现状及进展[J]. 中华血管外科杂志, 2023, 8(1): 58-63.
[3] Jackson, W.F. (2021) Calcium-Dependent Ion Channels and the Regulation of Arteriolar Myogenic Tone. Frontiers in Physiology, 12, Article 770450. [Google Scholar] [CrossRef] [PubMed]
[4] Kiyooka, T., Ohanyan, V., Yin, L., Pung, Y.F., Chen, Y., Chen, C., et al. (2022) Mitochondrial DNA Integrity and Function Are Critical for Endothelium-Dependent Vasodilation in Rats with Metabolic Syndrome. Basic Research in Cardiology, 117, Article No. 3. [Google Scholar] [CrossRef] [PubMed]
[5] 余文静, 李著华. 中医阴阳平衡与机体氧化还原态平衡关系的初探[J]. 时珍国医国药, 2010, 21(11): 2963-2965.
[6] Moore, K.J., Sheedy, F.J. and Fisher, E.A. (2013) Macrophages in Atherosclerosis: A Dynamic Balance. Nature Reviews Immunology, 13, 709-721. [Google Scholar] [CrossRef] [PubMed]
[7] Li, X., Yang, Y., Zhang, B., Lin, X., Fu, X., An, Y., et al. (2022) Lactate Metabolism in Human Health and Disease. Signal Transduction and Targeted Therapy, 7, Article No. 305. [Google Scholar] [CrossRef] [PubMed]
[8] 徐强, 孙郑青, 元绍爽, 等. 基于“痹岩同归”浅析从癥瘕积聚论治糖尿病性下肢血管斑块性病变[J]. 四川中医, 2024, 42(2): 42-45.
[9] Tuenter, A., Selwaness, M., Arias Lorza, A., Schuurbiers, J.C.H., Speelman, L., Cibis, M., et al. (2016) High Shear Stress Relates to Intraplaque Haemorrhage in Asymptomatic Carotid Plaques. Atherosclerosis, 251, 348-354. [Google Scholar] [CrossRef] [PubMed]
[10] Tardajos Ayllon, B., Bowden, N., Souilhol, C., Darwish, H., Tian, S., Duckworth, C., et al. (2025) Endothelial C-Rel Orchestrates Atherosclerosis at Regions of Disturbed Flow through Crosstalk with Txnip-P38 and Non-Canonical NF-κB Pathways. Cardiovascular Research, 121, 748-759. [Google Scholar] [CrossRef] [PubMed]
[11] Wang, X. and He, B. (2024) Endothelial Dysfunction: Molecular Mechanisms and Clinical Implications. MedComm, 5, e651. [Google Scholar] [CrossRef] [PubMed]
[12] Hansson, G.K. (2005) Inflammation, Atherosclerosis, and Coronary Artery Disease. New England Journal of Medicine, 352, 1685-1695. [Google Scholar] [CrossRef] [PubMed]
[13] Fuster, V., Moreno, P.R., Fayad, Z.A., Corti, R. and Badimon, J.J. (2005) Atherothrombosis and High-Risk Plaque. Journal of the American College of Cardiology, 46, 937-954. [Google Scholar] [CrossRef] [PubMed]
[14] Davies, P.F. (2008) Hemodynamic Shear Stress and the Endothelium in Cardiovascular Pathophysiology. Nature Clinical Practice Cardiovascular Medicine, 6, 16-26. [Google Scholar] [CrossRef] [PubMed]
[15] An, Y., Xu, B., Wan, S., Ma, X., Long, Y., Xu, Y., et al. (2023) The Role of Oxidative Stress in Diabetes Mellitus-Induced Vascular Endothelial Dysfunction. Cardiovascular Diabetology, 22, Article No. 237. [Google Scholar] [CrossRef] [PubMed]
[16] 谭梦瑶. 近十年营卫学说研究进展[J]. 中医临床研究, 2024, 16(3): 121-128.
[17] 袁晓雯, 姜楠, 柏冬, 等. 桂枝汤调控免疫和肠道菌群抗动脉粥样硬化的作用[J]. 中国实验方剂学杂志, 2021, 27(4): 24-29.
[18] 杨红, 周鸿飞. 调和营卫法中药汤剂对短暂性脑缺血发作患者血清相关因子水平的影响[J]. 中国现代药物应用, 2021, 15(6): 212-214.
[19] 何建成, 王利. 中医药对血管新生促进或抑制作用的研究进展[J]. 西安交通大学学报(医学版), 2018, 39(6): 775-778.
[20] 满玉晶, 张萌, 吴效科, 等. 桂枝茯苓丸的药理作用及其临床应用[J]. 中医临床研究, 2017, 9(28): 141-143.
[21] 邵浥为, 陈岩. 基于网络药理学探讨二陈汤治疗高脂血症的分子机制[J]. 中医临床研究, 2023, 15(10): 34-40.
[22] 李静, 刘晖, 廖文力. 二陈汤合四物汤加减治疗高脂血症合并颈动脉粥样硬化斑块的临床观察[J]. 中医临床研究, 2019, 11(11): 37-39.
[23] 刘玥, 殷惠军, 史大卓, 等. 活血化瘀中药与抗血小板治疗[J]. 科学通报, 2014, 59(8): 647-655.
[24] Feehan, J., Hariharan, R., Buckenham, T., Handley, C., Bhatnagar, A., Baba, S.P., et al. (2022) Carnosine as a Potential Therapeutic for the Management of Peripheral Vascular Disease. Nutrition, Metabolism and Cardiovascular Diseases, 32, 2289-2296. [Google Scholar] [CrossRef] [PubMed]