地塞米松眼内植入剂反复进入前房保守治疗成功一例
A Case of Successful Conservative Treatment for Repeated Migration of Dexamethasone Intravitreal Implant into the Anterior Chamber
DOI: 10.12677/acm.2025.1571997, PDF,   
作者: 赵艺卓:滨州医学院第二临床医学院,山东 烟台;于欣欣:山东第二医科大学临床医学院,山东 潍坊;马路生*:青岛大学附属烟台毓璜顶医院眼科,山东 烟台
关键词: 地塞米松眼内植入剂黄斑囊样水肿玻璃体切除术后Dexamethasone Intraocular Implant Cystic Macular Edema After Vitrectomy
摘要: 本文报道1例由于左眼晶状体不全脱位行晶状体切割、玻璃体切割联合人工晶体悬吊手术的患者,术后11个月出现左眼黄斑区囊样水肿(Cystoid macular edema, CME),行地塞米松植入剂(Ozurdex)玻璃体药物注射术,术后Ozurdex两次进入前房,经保守治疗成功将其稳定在玻璃体腔内。
Abstract: This paper reports a case of lens cutting, vitrectomy combined with intraocular lens suspension due to incomplete dislocation of the left eye. Cystoid macular edema (CME) occurred 11 months after operation, and Ozurdex was injected into the vitreous cavity. After operation, Ozurdex entered the anterior chamber twice and was successfully stabilized in the vitreous cavity after conservative treatment.
文章引用:赵艺卓, 于欣欣, 马路生. 地塞米松眼内植入剂反复进入前房保守治疗成功一例[J]. 临床医学进展, 2025, 15(7): 366-370. https://doi.org/10.12677/acm.2025.1571997

参考文献

[1] Celik, N., Khoramnia, R., Auffarth, G.U., et al. (2020) Complications of Dexamethasone Implants: Risk Factors, Prevention, and Clinical Management. International Journal of Ophthalmology, 13, 1612-1620. [Google Scholar] [CrossRef] [PubMed]
[2] Majumder, P., Palkar, A., Pathare, N. and Biswas, J. (2019) Anterior Chamber Migration of a Sustained-Release Dexamethasone Intravitreal Implant: A Case Report and Review of Literature. Oman Journal of Ophthalmology, 12, 133-137. [Google Scholar] [CrossRef] [PubMed]
[3] Chang-Lin, J., Attar, M., Acheampong, A.A., Robinson, M.R., Whitcup, S.M., Kuppermann, B.D., et al. (2011) Pharmacokinetics and Pharmacodynamics of a Sustained-Release Dexamethasone Intravitreal Implant. Investigative Opthalmology & Visual Science, 52, 80-86. [Google Scholar] [CrossRef] [PubMed]
[4] Pacella, F., Agostinelli, E., Carlesimo, S.C., Nebbioso, M., Secondi, R., Forastiere, M., et al. (2016) Management of Anterior Chamber Dislocation of a Dexamethasone Intravitreal Implant: A Case Report. Journal of Medical Case Reports, 10, Article No. 282. [Google Scholar] [CrossRef] [PubMed]
[5] Baker, E. (2021) Is There a Safe and Effective Way to Wean Patients off Long‐Term Glucocorticoids? British Journal of Clinical Pharmacology, 87, 12-22. [Google Scholar] [CrossRef] [PubMed]
[6] Rosenblatt, A., Udaondo, P., Cunha-Vaz, J., Sivaprasad, S., Bandello, F., Lanzetta, P., et al. (2020) A Collaborative Retrospective Study on the Efficacy and Safety of Intravitreal Dexamethasone Implant (Ozurdex) in Patients with Diabetic Macular Edema. Ophthalmology, 127, 377-393. [Google Scholar] [CrossRef] [PubMed]
[7] Liew, G., Moore, A.T., Webster, A.R. and Michaelides, M. (2015) Efficacy and Prognostic Factors of Response to Carbonic Anhydrase Inhibitors in Management of Cystoid Macular Edema in Retinitis Pigmentosa. Investigative Ophthalmology & Visual Science, 56, 1531-1536. [Google Scholar] [CrossRef] [PubMed]
[8] Mayer, W.J., Remy, M., Wolf, A., Kook, D., Kampik, A., Ulbig, M., et al. (2012) Comparison of Intravitreal Bevacizumab Upload Followed by a Dexamethasone Implant versus Dexamethasone Implant Monotherapy for Retinal Vein Occlusion with Macular Edema. Ophthalmologica, 228, 110-116. [Google Scholar] [CrossRef] [PubMed]
[9] Reid, G.A., Sahota, D.S. and Sarhan, M. (2015) Observed Complications from Dexamethasone Intravitreal Implant for the Treatment of Macular Edema in Retinal Vein Occlusion over 3 Treatment Rounds. Retina, 35, 1647-1655. [Google Scholar] [CrossRef] [PubMed]
[10] Casati, S., Bruni, E. and Marchini, G. (2016) Retinal and Vitreous Hemorrhage after Traumatic Impact of Dexamethasone Implant in a Vitrectomized Eye. European Journal of Ophthalmology, 26, e55-e57. [Google Scholar] [CrossRef] [PubMed]
[11] Bernal, L. and Estévez, B. (2016) Toxicidad corneal tras migración de Ozurdex® a cámara anterior. Archivos de la Sociedad Española de Oftalmología, 91, 292-294. [Google Scholar] [CrossRef] [PubMed]
[12] Vela, J.I., Crespí, J. and Andreu, D. (2012) Repositioning of Dexamethasone Intravitreal Implant (Ozurdex®) Migrated into the Anterior Chamber. International Ophthalmology, 32, 583-584. [Google Scholar] [CrossRef] [PubMed]