聚桂醇泡沫局部注射治疗口腔颌面部脉管畸形52例临床分析

Clinical Analysis of 52 Cases of Vascular Malformation in Oral and Maxillofacial Region Treated by Local Injection of Lauromacrogol Foam

摘要: 目的：分析聚桂醇泡沫局部注射治疗口腔颌面部脉管畸形的效果。方法：选取2019年1月至2023年8月在我科诊断为口腔颌面部脉管畸形的患者共52例，给予聚桂醇泡沫注射后3~12个月随访复查，比较治疗前后瘤体体积变化，分析有效率以及不良反应发生情况。结果：口腔颌面部脉管畸形注射聚桂醇泡沫后瘤体明显缩小(P < 0.001)，有效率达98.1%，除局部肿胀疼痛及胃肠道反应外无其他不良反应发生。结论：聚桂醇泡沫局部注射治疗口腔颌面部脉管畸形安全有效，可明显缩小瘤体体积，避免外科手术风险。

Abstract: Objective: To analyze the effect of local injection of lauromacrogol foam in the treatment of vascular malformations in oral and maxillofacial regions. Methods: A total of 52 patients with vascular malformations in the oral and maxillofacial region diagnosed in our department from January 2019 to August 2023 were selected. They were followed up and re-examined 3 to 12 months after the injection of lauromacrogol foam. The changes in tumor volume before and after treatment were compared, and the effective rate and occurrence of adverse reactions were analyzed. Results: After injection of lauromacrogol foam into vascular malformations in oral and maxillofacial region, the tumor size was significantly reduced (P < 0.001), and the effective rate was 98.1%; no other adverse reactions occurred except for local swelling, pain, and gastrointestinal reactions. Conclusion: Local injection of lauromacrogol foam is safe and effective in the treatment of vascular malformations in oral and maxillofacial region, which can significantly reduce the tumor volume and avoid surgical risks.