MDT联合干预对阿尔茨海默病患者转归的影响
Influence of Multidisciplinary Team (MDT) Joint Intervention on the Outcomes of Alzheimer’s Disease Patients
DOI: 10.12677/acm.2025.1582232, PDF,    科研立项经费支持
作者: 时 誉, 何 俐*：新疆医科大学附属中医医院脑病一科，新疆 乌鲁木齐；李 琴：新疆和田县人民医院感染办，新疆 和田
关键词: 多学科协作模式；联合干预；阿尔茨海默病；转归；Multidisciplinary Team (MDT)； Joint Intervention； Alzheimer’s Disease； Outcome
摘要: 目的：研究多学科协作模式(MDT)对阿尔茨海默病(AD)患者转归的影响。方法：选取我院2023年1~12月100例AD患者，纳入MDT干预组与非MDT干预组，每组50例；MDT干预组实施MDT干预，非MDT干预组未实施MDT干预，随访12个月，对比2组的认知功能(MMSE、MOCA得分)、日常生活能力(ADL得分)、负性情绪(HAMD、HAMA得分)、神经精神行为(NPI得分)。结果：MDT干预组干预后的MMSE、MOCA得分高于非MDT干预组，P < 0.05。MDT干预组干预后的ADL得分高于非MDT干预组，P < 0.05。MDT干预组干预后的HAMD、HAMA得分低于非MDT干预组，P < 0.05。MDT干预组干预后的NPI-1、NPI-2得分低于非MDT干预组，P < 0.05。结论：MDT下联合干预对AD患者转归具有积极影响，可提高认知功能与日常生活能力，减轻负性情绪，改善神经精神行为。
Abstract: Objective: To investigate the impact of multidisciplinary team (MDT) on the outcomes of patients with Alzheimer’s disease (AD). Methods: A total of 100 AD patients admitted to our hospital from January to December 2023 were selected and divided into the MDT intervention group and non-MDT intervention group, with 50 cases in each group. The MDT intervention group received MDT intervention, while the non-MDT intervention group did not. After a 12-month follow-up, the cognitive function (MMSE and MOCA scores), activities of daily living (ADL score), negative emotions (HAMD and HAMA scores), and neuropsychiatric behaviors (NPI scores) were compared between the two groups. Results: The MMSE and MOCA scores of the MDT intervention group after intervention were higher than those of the non-MDT intervention group, with P < 0.05. The ADL score of the MDT intervention group after intervention was higher than that of the non-MDT intervention group, with P < 0.05. The HAMD and HAMA scores of the MDT intervention group after intervention were lower than those of the non-MDT intervention group, with P < 0.05. The NPI-1 and NPI-2 scores of the MDT intervention group after intervention were lower than those of the non-MDT intervention group, with P < 0.05. Conclusion: The combined intervention under MDT has a positive impact on the outcomes of AD patients, which can improve cognitive function and activities of daily living, alleviate negative emotions, and improve neuropsychiatric behaviors.
文章引用：时誉, 李琴, 何俐. MDT联合干预对阿尔茨海默病患者转归的影响[J]. 临床医学进展, 2025, 15(8): 284-291. https://doi.org/10.12677/acm.2025.1582232

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