ECMO联合西维来司他纳治疗甲型流感病毒相关急性呼吸窘迫综合征的临床综述

Clinical Review of ECMO Combined with Sodium Sivelestat in the Treatment of Acute Respiratory Distress Syndrome Associated with Influenza A Virus

摘要: 甲型流感病毒常侵犯呼吸系统，出现呼吸道感染症状，可进展为急性呼吸窘迫综合征(Acute Respiratory Distress Syndrome, ARDS)，患者出现呼吸窘迫及顽固性低氧血症，加重患者死亡风险。目前可给予ECMO支持治疗作为呼吸衰竭的最终治疗手段；给予西维来司他纳抗炎、改善患者氧合指数。本综述将系统地探讨两者联合的治疗方案，并阐述一例经ECMO联合西维来司他纳治疗甲型流感病毒相关ARDS的成功临床病例。

Abstract: Influenza A virus often invades the respiratory system, causing respiratory tract infection symptoms, which can progress to acute respiratory distress syndrome (ARDS). Patients may experience respiratory distress and persistent hypoxemia, increasing the risk of death. Currently, ECMO support therapy can be provided as the ultimate treatment for respiratory failure; sodium Sivelestat sodium can be given to reduce inflammation and improve the patient's oxygenation index. This review will systematically explore the combined treatment plan of the two and describe a successful clinical case of treating ARDS related to influenza A virus with ECMO combined with sodium Sivelestat.