原发性腹膜后肿瘤患者围术期生存质量调查分析

Analysis of the Perioperative Quality of Life of Patients with Primary Retroperitoneal Tumors

摘要: 目的：探究影响原发性腹膜后肿瘤患者围术期生存质量的主要因素。方法：对2021年12月至2024年12月在上海长海医院泌尿外科腹膜后肿瘤组经手术治疗的腹膜后恶性肿瘤患者进行EORTCQLQ-C30简体中文版量表术前、术后1周和术后1月的问卷调查，并对患者社会心理改善程度进行多元线性回归分析。结果：术后显著提高患者躯体功能、情绪功能、角色功能和社会功能，同时改善疼痛、失眠和便秘(P < 0.05)；而没有改变患者认知功能、疲劳、恶心呕吐、气促、食欲丧失、腹泻、经济困难(P > 0.05)。并且患者社会心理改善程度与疼痛程度和功能改善密切相关(P < 0.05)。结论：积极的外科手术帮助患者获得功能改善和心理支持，从而提高围术期患者的生存质量。

Abstract: Objective: To explore the main factors influencing the perioperative quality of life of patients with primary retroperitoneal tumors. Methods: A questionnaire survey using the EORTC QLQ-C30 Simplified Chinese version was conducted on patients with retroperitoneal malignant tumors who underwent surgery in the retroperitoneal tumor group of the Department of Urology, Changhai Hospital, Shanghai from December 2021 to December 2024, before surgery, one week after surgery, and one month after surgery. A multiple linear regression analysis was performed on the degree of improvement in patients’ social and psychological aspects. Results: Surgery significantly improved patients’ physical function, emotional function, role function, and social function, and also alleviated pain, insomnia, and constipation (P < 0.05); however, it did not change cognitive function, fatigue, nausea and vomiting, shortness of breath, loss of appetite, diarrhea, or economic difficulties (P > 0.05). Moreover, the degree of improvement in patients’ social and psychological aspects was closely related to the degree of pain and functional improvement (P < 0.05). Conclusion: Active surgical intervention helps patients achieve functional improvement and psychological support, thereby enhancing the quality of life of perioperative patients.