VSD联合植皮术在深度烧伤中的研究进展
Research Progress on VSD Combined with Skin Grafting in the Treatment of Deep Burns
DOI: 10.12677/acm.2025.1582266, PDF,   
作者: 王超超, 李耀文:延安大学医学院,陕西 延安;席云峰*:延安大学第二附属医院(榆林市第一医院)烧伤整形皮肤外科,陕西 榆林
关键词: VSD深度烧伤植皮术VSD Deep Burns Skin Grafting
摘要: 深度烧伤作为严重创伤,会对患者皮肤、组织及全身健康产生极大影响,治疗难度高且面临诸多挑战。VSD联合植皮技术为深度烧伤治疗带来新的突破,成为临床与科研重点关注领域。VSD技术借助负压封闭引流,可有效清除创面渗出物、坏死组织和细菌,改善局部微循环,营造适宜植皮的创面环境,还能促进肉芽组织生长。大量临床研究和实践表明,相较于传统治疗手段,VSD联合植皮技术优势显著,能显著缩短创面愈合时间,降低感染发生率,提升植皮成活率,减少患者换药痛苦与住院时长,在促进患者康复、减轻经济负担方面成效突出。本文全面梳理VSD联合植皮技术在深度烧伤治疗中的原理、操作要点、临床应用效果、优势及面临的挑战,旨在为临床医生提供系统、全面的技术参考,推动该技术在深度烧伤治疗中的规范化、精准化应用,进一步提升深度烧伤的治疗水平,改善患者预后。
Abstract: Deep burns, as a severe form of trauma, exert a significant impact on the patient’s skin, tissues, and overall health. Their treatment is highly challenging and faces numerous difficulties. Vacuum Sealing Drainage (VSD) combined with skin grafting technology has brought a new breakthrough in the treatment of deep burns, becoming a key focus area in both clinical practice and research. VSD technology utilizes negative pressure closed drainage to effectively remove wound exudate, necrotic tissue, and bacteria, improve local microcirculation, create a wound environment conducive to skin grafting, and promote the growth of granulation tissue. Extensive clinical research and practice demonstrate that, compared to traditional treatment methods, VSD combined with skin grafting offers significant advantages. It can markedly shorten wound healing time, reduce the incidence of infection, improve skin graft survival rates, decrease patient suffering during dressing changes, and shorten hospital stays. It demonstrates outstanding efficacy in promoting patient recovery and alleviating economic burden. This article comprehensively reviews the principles, key operational points, clinical application outcomes, advantages, and existing challenges of VSD combined with skin grafting technology in the treatment of deep burns. The aim is to provide clinicians with a systematic and comprehensive technical reference, promote the standardized and precise application of this technology in deep burn treatment, further enhance the therapeutic level for deep burns, and improve patient prognosis.
文章引用:王超超, 席云峰, 李耀文. VSD联合植皮术在深度烧伤中的研究进展[J]. 临床医学进展, 2025, 15(8): 551-560. https://doi.org/10.12677/acm.2025.1582266

参考文献

[1] 林岳森, 崔承硕, 胡加林. 负压封闭引流技术联合植皮在深度烧伤创面修复中的应用[J]. 浙江创伤外科, 2025, 30(4): 624-627.
[2] Liu, M.D., Yang, X.K., Han, F., et al. (2018) Strategy for Wound Repair of Skin and Soft Tissue Defect and Systematic Rehabilitation Treatment for Functional Reconstruction of Patients with Severe Burn or Trauma on Knees. Chinese Journal of Burns, 34, 266-270.
[3] 陈梦杰, 陈建崇, 方明星, 等. 负压封闭引流结合游离植皮疗法对深度烧伤患者创面愈合率及愈合时间、疼痛程度的影响[J]. 哈尔滨医药, 2025, 45(0): 76-78.
[4] Chen, S., Zheng, L.W., Liu, W., et al. (2019) Clinical Effects of Artificial Dermis Combined with Vacuum Sealing Drainage and Autologous Split-Thickness Skin Graft in Repair of Scar Contracture Deformity after Extensive Burn. Chinese Journal of Burns, 35, 608-610.
[5] Yuan, Y., Zhong, X., Zhang, J., Shen, C., Huang, G., Zhang, J., et al. (2023) Artificial Dermis Combined with Split-Thickness Skin Autograft in the Treatment of Hand Thermal Compression Wounds: A Single Center Case-Control Study. Frontiers in Surgery, 10, Article 1304333. [Google Scholar] [CrossRef] [PubMed]
[6] Jiao, H., Tian, T., Chen, C., et al. (2022) Effect of Vacuum Sealing Drainage Plus Skin Grafting on Deep Burns and Analysis of Risk Factors for Postoperative Infection. American Journal of Translational Research, 14, 7477-7486.
[7] Yuan, X.-., Zhang, X., Fu, Y., Tian, X., Liu, Y., Xiao, J., et al. (2016) Sequential Therapy with “Vacuum Sealing Drainage-Artificial Dermis Implantation-Thin Partial Thickness Skin Grafting” for Deep and Infected Wound Surfaces in Children. Orthopaedics & Traumatology: Surgery & Research, 102, 369-373. [Google Scholar] [CrossRef] [PubMed]
[8] 吕占武, 王聪静. 封闭式负压引流联合游离植皮术对深度烧伤感染创面的效果研究[J]. 深圳中西医结合杂志, 2021, 31(18): 125-127.
[9] 戚伟伟, 陈晨, 徐飞, 等. 负压封闭引流技术对颈部及躯干深度烧伤植皮修复患儿生活质量和血清炎症因子的影响[J]. 现代生物医学进展, 2021, 21(17): 3336-3340.
[10] 曹凤, 李升红, 黄海玲, 等. 削痂植皮术后结合负压封闭引流在深度烧伤患者中的应用效果及对血清致痛因子及炎性因子的影响[J]. 现代生物医学进展, 2023, 23(7): 1324-1328.
[11] 周文涛, 何国, 张文仕, 等. 封闭负压引流术在烧伤植皮中的应用效果研究[J]. 白求恩医学杂志, 2015, 13(1): 12-13.
[12] Sun, T., Ying, W., Wang, S., Chen, C., Sun, P. and Tan, J. (2021) Clinical Application of Vacuum Sealing Drainage for the Treatment of Deep Burn Wounds. The American Surgeon™, 89, 1018-1023. [Google Scholar] [CrossRef] [PubMed]
[13] 杨军, 华烨. 湿润烧伤膏联合负压封闭引流在慢性难愈合创面植皮术后的应用效果分析[J]. 中国烧伤创疡杂志, 2020, 32(5): 331-334.
[14] Li, Y., Zhang, Z., Liu, J., Wu, Z., Sun, X., Zhao, Y., et al. (2022) Analysis of the Therapeutic Effect of Artificial Leather Embedding Combined with Fascial Sleeve Flap Transplantation on Chronic Wounds of Lower Limbs with Bone and Plate Exposure. BMC Surgery, 22, Article No. 69. [Google Scholar] [CrossRef] [PubMed]
[15] 赵凤娥, 李振强, 梁贤芳. 负压封闭引流技术在手足外科复杂创面中的应用效果[J]. 中国当代医药, 2015, 22(18): 188-191.
[16] 杨广远, 李超, 李开通. 负压封闭引流技术联合植皮术在深度烧伤创面修复中的应用研究[J]. 家庭医药∙就医选药, 2018(6): 114.
[17] Cheng, L., Du, W.L., Zhang, Y., et al. (2021) Staged Repair Strategy for Chronic Sacrococcygeal Radiation Ulcer. Chinese Journal of Burns, 37, 225-231.
[18] 杨大民. 负压技术与打包技术在瘢痕切除皮片移植固定中对比的回顾性研究[D]: [硕士学位论文]. 贵阳: 贵州医科大学, 2022.
[19] 孙充洲, 王帅道, 赵婷慧, 等. 二次负压封闭引流对小儿大面积深II度烧伤创面愈合的疗效研究[J]. 中国美容医学, 2019, 28(3): 31-33.
[20] 地里夏提·库尔班, 陈召, 刘小龙. 供氧条件下负压封闭引流联合自体皮移植治疗难愈性糖尿病足溃疡的临床研究[J]. 中华损伤与修复杂志(电子版), 2022, 17(1): 25-31.