miR-214在骨质疏松症中的作用及中医药干预研究进展
Research Progress on the Role of miR-214 in Osteoporosis and the Intervention of Traditional Chinese Medicine
DOI: 10.12677/tcm.2025.148493, PDF,   
作者: 邱婧怡, 董重阳*：内蒙古医科大学中医学院，内蒙古 呼和浩特
关键词: miR-214；骨质疏松症；中医药；miR-214； Osteoporosis； Traditional Chinese Medicine (TCM)
摘要: 骨质疏松症是指骨量降低，骨组织微结构破坏使骨强度减低，使骨折的危险性增加的一种严重危害老年人健康的常见骨骼疾病。近年来发现miR-214参与骨代谢，在骨质疏松症的发病过程中miR-214异常表达可以引起骨质疏松症的发展，其通过调控成骨及破骨细胞的功能，调节骨代谢过程。目前骨质疏松症的治疗中其药物仍存在一定的毒副作用及服药依从性差等问题，而中医药治疗骨质疏松症有着自身的特点和优势。本文旨在通过梳理近十年来的相关文献进行综述，以期为后续研究提供参考依据。
Abstract: Osteoporosis refers to the decrease in bone mass, the destruction of bone tissue microstructure, which reduces bone strength, and makes fracture risk. An increase in a common bone disease that seriously endangers the health of older adults. In recent years, it has been found that miR-214 is involved in bone metabolism, and abnormal expression of miR-214 can cause the development of osteoporosis during the pathogenesis of osteoporosis, which regulates the bone metabolism process by regulating the function of osteoblasts and osteoclasts. At present, in the treatment of osteoporosis, there are still certain problems such as toxic side effects and poor medication compliance, and traditional Chinese medicine has its own characteristics and advantages in the treatment of osteoporosis. The purpose of this paper is to review the relevant literature in the past ten years, in order to provide a reference for subsequent research.
文章引用：邱婧怡, 董重阳. miR-214在骨质疏松症中的作用及中医药干预研究进展[J]. 中医学, 2025, 14(8): 3333-3340. https://doi.org/10.12677/tcm.2025.148493

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