维生素在孤独症谱系障碍中的作用研究进展
Research Progress on the Role of Vitamins in Autism Spectrum Disorder
DOI: 10.12677/acm.2025.1582294, PDF,    科研立项经费支持
作者: 杜春雨：延安大学延安医学院，陕西 延安；李兴珍*：延安大学附属医院儿科，陕西 延安
关键词: 孤独症谱系障碍(ASD)；维生素A；维生素B；维生素C；维生素D；维生素E；Autism Spectrum Disorder (ASD)； Vitamin A； Vitamin B； Vitamin C； Vitamin D； Vitamin E
摘要: 孤独症谱系障碍(Autism Spectrum Disorder, ASD)作为一种复杂的以社会沟通和社会互动障碍以及重复刻板行为为主要症状的神经发育障碍性疾病，其病因和发病机制尚不明确。近年来研究发现，ASD患者体内多种维生素的缺乏，可能是导致患者认知功能下降和语言功能障碍的重要原因。本文采用PRISMA指南，系统检索和筛选维生素的基本代谢特点，维生素A、D、C、E以及维生素B1、B2、B6、B9、B12缺乏与ASD的关系，以及补充维生素改善ASD症状等方面的研究，旨在探讨营养干预措施对提高ASD患儿生活质量的潜在价值，以期为今后的研究及治疗提供新的思路，寻找新的作用靶点，同时为临床实践提供更多的指导，帮助医生和家长更有效地支持这一特殊群体儿童的健康发展。
Abstract: Autism Spectrum Disorder (ASD), as a complex neurodevelopmental disorder with social communication and social interaction disorder and repetitive stereotyped behavior as the main symptoms, its etiology and pathogenesis are not clear. Recent studies have found that the deficiency of multiple vitamins in ASD patients may be an important cause of cognitive decline and language dysfunction in patients. This paper uses the PRISMA guidelines to systematically search for and screen the research on the basic metabolic characteristics of vitamins, as well as the relationship between vitamins A, D, C, E, vitamins B1, B2, B6, B9, B12 deficiency and ASD, and the effects of vitamin supplementation on improving ASD symptoms, aiming to explore the potential value of nutritional interventions to improve the quality of life of children with ASD, in order to provide new ideas for future research and treatment, find new targets, and provide more guidance for clinical practice, to help doctors and parents more effectively support the healthy development of this special group of children.
文章引用：杜春雨, 李兴珍. 维生素在孤独症谱系障碍中的作用研究进展[J]. 临床医学进展, 2025, 15(8): 762-771. https://doi.org/10.12677/acm.2025.1582294

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