枢筋理论指导下水筋针治疗膝骨关节炎的临床观察

Clinical Observation of Water Tendon Acupuncture for Knee Osteoarthritis Guided by the Theory of Shu-Jin

摘要: 目的：分析膝骨关节炎(KOA)患者选取枢筋理论指导下水筋针为治疗方案的临床优势，为该病的临床治疗提供参考。方法：前瞻性选取83例我院2022年1月~2024年12月收治的KOA患者，分为对照组(42例失访2例，纳入40例，常规 + 玻璃酸钠关节腔注射)与试验组(41例失访1例，纳入40例，对照组 + 枢筋理论指导下水筋针)，分组依据：随机数字表法，均在治疗后1个月进行随访，比较两组治疗后1月的疗效，治疗前、治疗后1个月疾病疼痛/严重程度与膝关节活动度、炎症指标，治疗及随访期间不良反应。结果：组间比较，治疗后1个月两组疗效等级有差异，且试验组的总有效率更高；治疗后1个月试验组视觉模拟评分法(VAS)、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分降低、最大主动关节活动度(AROM)升高，关节液基质金属蛋白酶-3 (MMP-3)、外周血红细胞沉降率(ESR)及血清C反应蛋白(CRP)水平降低，关节液基质金属蛋白酶抑制物-1 (TIMP-1)升高，P < 0.05。试验组、对照组治疗及随访期间的不良反应总发生率比较无差异，P > 0.05。结论：枢筋理论指导下水筋针治疗KOA疗效显著，可有效缓解患者疼痛，改善膝关节功能，减轻炎症反应，且安全性良好。

Abstract: Objective: To analyze the clinical advantages of treating knee osteoarthritis (KOA) patients with the Water tendon acupuncture guided by the theory of Shu-jin, providing reference for the clinical treatment of this disease. Methods: A prospective study was conducted on 83 patients with KOA admitted to our hospital from January 2022 to December 2024. The patients were divided into a control group (42 cases, with 2 lost to follow-up and 40 included; treated with conventional therapy plus intra-articular injection of sodium hyaluronate) and an experimental group (41 cases, with 1 lost to follow-up and 40 included; treated with the control group’s therapy plus Water tendon acupuncture guided by the theory of Shu-jin). The grouping was based on the random number table method. Follow-up was conducted one month after treatment for both groups. The therapeutic effects one month after treatment, disease pain/severity, knee joint range of motion, inflammatory markers before and one month after treatment, as well as adverse reactions during treatment and follow-up, were compared between the two groups. Results: Comparison between the groups showed differences in the therapeutic effect levels one month after treatment, with a higher total effective rate in the experimental group. One month after treatment, the experimental group exhibited a decrease in Visual Analog Scale (VAS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores, an increase in active range of motion (AROM), a decrease in synovial fluid matrix metalloproteinase-3 (MMP-3), peripheral blood erythrocyte sedimentation rate (ESR), and serum C-reactive protein (CRP) levels, and an increase in synovial fluid tissue inhibitor of metalloproteinase-1 (TIMP-1), with P < 0.05. There was no significant difference in the incidence of adverse reactions during treatment and follow-up between the experimental and control groups (P > 0.05). Conclusion: Water tendon acupuncture therapy guided by the theory of Shu-jin demonstrates significant therapeutic efficacy in treating KOA. It can effectively alleviate pain, improve knee joint function, and reduce inflammatory responses, with good safety.