经典名方大柴胡汤历史沿革及现代应用研究

Research on the Historical Evolution and Modern Application of the Classic Recipe Da Chai Hu Tang

摘要: 2型糖尿病(T2DM)发病率呈逐年上升趋势，其发病机制复杂，涉及胰岛素抵抗、胰岛β细胞损伤及多种代谢性疾病。现代医学虽然在控制血糖和并发症方面取得长足的进步，但是长期治疗仍然面临着副作用大、患者依从性差等问题。近年来，随着中医药在慢性病防治中的作用日益受到重视，经方大柴胡汤对2型糖尿病的治疗作用备受关注。大柴胡汤源于《伤寒论》，组方巧妙，具有疏肝理胃、通气机之功效，基于“脾胃为后天之本”、“中焦为气机升降枢纽”理论，为2型糖尿病的防治提供新思路。

Abstract: The incidence of type 2 diabetes mellitus (T2DM) is increasing year by year, and its pathogenesis is complex, involving insulin resistance, pancreatic β cell damage and a variety of metabolic diseases. Although modern medicine has made great strides in controlling blood sugar and complications, long-term treatment still faces problems such as high side effects and poor patient compliance. In recent years, with the increasing attention to the role of traditional Chinese medicine in the prevention and treatment of chronic diseases, the therapeutic effect of the Classic Recipe Da Chai Hu Tang on type 2 diabetes has attracted much attention. The classic recipe Da Chai Hu Tang originated from the “Treatise on Typhoid Fever”, and the formula was ingenious, which had the effect of loosening the liver and stomach, and ventilating the machine. Based on the theories of “the spleen and stomach are the foundation of the acquired” and “the middle jiao is the lifting hub of the qi machine”, it provides new ideas for the prevention and treatment of type 2 diabetes.