儿童重症百日咳血清预测指标研究进展
Research Progress on Serum Predictive Metrics of Severe Pertussis in Children
DOI: 10.12677/acm.2025.1582327, PDF,   
作者: 曾 洁, 贾 薇：吉首大学医学院，湖南 吉首；罗启林*：吉首大学第四临床学院儿科，湖南 怀化
关键词: 重症百日咳；病理生理；预测指标；Severe Pertussis； Pathophysiology； Predictive Metrics
摘要: 百日咳(pertussis)是一种极具传染性的呼吸道疾病，近年来，该病出现了“百日咳再现”现象，导致部分地区百日咳疫情爆发。重症患者中，未接种或未完全接种百日咳疫苗的婴幼儿占多数。这些患者的临床症状往往不典型，容易导致漏诊或误诊，且易引发严重的并发症，甚至可能危及生命。本文旨在回顾近年来关于儿童重症百日咳的研究，探讨其病理生理和血清预测指标，以期为临床实践和研究提供有益的参考。
Abstract: Pertussis is an extremely communicable respiratory infection, and in recent years, there has been a “re-emergence of whooping cough” in the disease, leading to an outbreak of pertussis in some areas. Most of the critically ill patients are infants who have not been vaccinated or have not been fully immunized against pertussis. The clinical symptoms of these patients are often atypical, which can easily lead to missed or misdiagnosed diagnoses, and can lead to serious complications and may even be life-threatening. The purpose of this article is to review the recent research on severe pertussis in children, discuss its pathogenesis and serum predictive metrics, and provide an advantageous reference for clinical practice and investigation.
文章引用：曾洁, 罗启林, 贾薇. 儿童重症百日咳血清预测指标研究进展[J]. 临床医学进展, 2025, 15(8): 1009-1015. https://doi.org/10.12677/acm.2025.1582327

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