糖尿病足患者的弗氏柠檬酸杆菌感染1例

A Case Report of Citrobacter freundii Infection in Patients with Diabetic Foot

摘要: 糖尿病足溃疡(DFU)指糖尿病患者因下肢神经和血管病变导致的足部感染、溃疡或深层组织的破坏。其主要表现为足部感觉异常、足畸形及足部缺血导致的疼痛、行走困难等，常合并感染、溃疡、坏疽甚至截肢等。早期表现为皮肤温度低、疼痛等下肢供血不足症状，感觉麻木、迟钝等周围神经病变症状，晚期足部出现肌肉、骨组织的坏死。本病例报告旨在强调由罕见病原体引起的DFU病例的创面愈合情况和抗生素敏感性，以便启动最佳的抗菌治疗。

Abstract: Diabetic foot ulcer (DFU) refers to foot infections, ulcers, or destruction of deep tissues caused by nerve and vascular lesions in the lower extremities in people with diabetes. It is mainly manifested as foot paresthesia, foot deformity and pain caused by foot ischemia, difficulty in walking, etc., often combined with infection, ulcers, gangrene and even amputation. In the early stage, it manifests as symptoms of insufficient blood supply to the lower limbs, such as low skin temperature and pain, and peripheral neuropathy symptoms, such as numbness and sluggishness. In the late stage, necrosis of muscle and bone tissue occurs in the foot. The purpose of this case report is to highlight wound healing status and antibiotic susceptibility in cases of DFU caused by rare pathogens in order to initiate optimal antimicrobial therapy.