血液透析并发脑出血的相关危险因素分析

Analysis of Related Risk Factors for Hemodialysis Complicated with Cerebral Hemorrhage

摘要: 目的：探讨终末期肾病患者行血液透析治疗并发脑出血的相关危险因素。方法：回顾性分析442例使用血液透析治疗的终末期肾病患者的病例资料，采用多因素Logistic回归分析血液透析并发脑出血组(n = 82)、未出血组(n = 360)。结果：二元Logistic回归结果显示，血液透析后收缩压(OR = 1.063)、抗凝药物种类(普通肝素OR = 0.090，低分子肝素OR = 0.037)、年龄(OR = 0.960)、血清钠(OR = 0.897)、血小板计数(OR = 0.990)是血液透析并发脑出血的独立影响因素(P < 0.05)。结论：血液透析后收缩压、抗凝药物种类、年龄、血清钠及血小板计数与血液透析并发脑出血有明显相关性，提醒我们对于易发生脑出血的人群血液透析时密切监测患者的相关影响因素指标并给予及时纠正。

Abstract: Objective: To explore the related risk factors of cerebral hemorrhage in patients with end-stage renal disease undergoing hemodialysis treatment. Methods: A retrospective analysis was conducted on the case data of 442 patients with end-stage renal disease treated with hemodialysis. The hemodialysis complicated with cerebral hemorrhage group (n = 82) and the non-hemorrhage group (n = 360) were analyzed using multivariate Logistic regression analysis. Result: The binary Logistic regression results showed that the systolic blood pressure after hemodialysis (OR = 1.063), the type of anticoagulant drugs (unfractionated heparin OR = 0.090, low molecular weight heparin OR = 0.037), age (OR = 0.960), serum sodium (OR = 0.897), and platelet count (OR = 0.990) were independent influencing factors for cerebral hemorrhage complicated with hemodialysis (P < 0.05). Conclusion: There is a significant correlation between systolic blood pressure after hemodialysis, the type of anticoagulant drugs, age, serum sodium and platelet count and cerebral hemorrhage complicated with hemodialysis. This reminds us that for the population prone to cerebral hemorrhage, we should closely monitor the relevant influencing factor indicators of patients during hemodialysis and give timely corrections.