新生儿气胸的诊治进展
Advances in Diagnosis and Treatment of Neonatal Pneumothorax
DOI: 10.12677/acm.2025.1582398, PDF,   
作者: 孔 舒：济宁医学院临床学院，山东 济宁；任雪云*：济宁医学院附属医院新生儿重症科，山东 济宁
关键词: 新生儿；气胸；呼吸窘迫；Newborn； Pneumothorax； Respiratory Distress Syndrome
摘要: 新生儿气胸(neonatal pneumothorax, NP)是新生儿常见的危急重症之一，发病急、进展快，如果不及时采取干预措施，可能会对患儿造成不良后果，甚至危及生命。因此，早期识别新生儿气胸是必要的，及时干预致命性气胸更能有效地降低新生儿死亡率、改善预后。不同胎龄之间气胸的危险因素、临床特点有所不同，各国家、地区的研究结论也并不一致。为更好地指导临床工作，提供更多参考价值，现对新生儿气胸的诊治进展予以综述。
Abstract: Neonatal pneumothorax is one of the most common critical diseases in neonates, which is rapid in onset and progression. If the intervention measures are not taken in time, it may cause adverse consequences to the children and even endanger their lives. Therefore, early identification of neonatal pneumothorax is necessary, timely intervention of fatal pneumothorax can effectively reduce neonatal mortality and improve prognosis. The risk factors and clinical characteristics of pneumothorax are different in different gestational ages, and the research conclusions of different countries and regions are not consistent. In order to better guide clinical work and provide more reference value, this article reviews the progress of diagnosis and treatment of neonatal pneumothorax.
文章引用：孔舒, 任雪云. 新生儿气胸的诊治进展[J]. 临床医学进展, 2025, 15(8): 1569-1574. https://doi.org/10.12677/acm.2025.1582398

参考文献

[1] Ayşe Tandırcıoğlu, Ü., Koral, Ü., Güzoğlu, N., Alan, S. and Aliefendioğlu, D. (2024) Differences in Possible Risk Factors, Treatment Strategies, and Outcomes of Neonatal Pneumothorax in Preterm and Term Infants. Turkish Archives of Pediatrics, 59, 87-92. [Google Scholar] [CrossRef] [PubMed]
[2] Hadzic, D., Skokic, F., Husaric, E., Alihodzic, H., Softic, D. and Kovacevic, D. (2019) Risk Factors and Outcome of Neonatal Pneumothorax in Tuzla Canton. Materia Socio Medica, 31, 66-70. [Google Scholar] [CrossRef] [PubMed]
[3] Vibede, L., Vibede, E., Bendtsen, M., Pedersen, L. and Ebbesen, F. (2016) Neonatal Pneumothorax: A Descriptive Regional Danish Study. Neonatology, 111, 303-308. [Google Scholar] [CrossRef] [PubMed]
[4] Acun, C., Nusairat, L., Kadri, A., Nusairat, A., Yeaney, N., Abu-Shaweesh, J., et al. (2021) Pneumothorax Prevalence and Mortality per Gestational Age in the Newborn. Pediatric Pulmonology, 56, 2583-2588. [Google Scholar] [CrossRef] [PubMed]
[5] Al Matary, A., Munshi, H.H., Abozaid, S., Qaraqei, M., Wani, T.A. and Abu-Shaheen, A.K. (2017) Characteristics of Neonatal Pneumothorax in Saudi Arabia: Three Years’ Experience. Oman Medical Journal, 32, 135-139. [Google Scholar] [CrossRef] [PubMed]
[6] Bhatia, R., Davis, P.G., Doyle, L.W., Wong, C. and Morley, C.J. (2011) Identification of Pneumothorax in Very Preterm Infants. The Journal of Pediatrics, 159, 115-120.e1. [Google Scholar] [CrossRef] [PubMed]
[7] Navaei, F., Aliabadi, B., Moghtaderi, M. and Kelishadi, R. (2010) Predisposing Factors, Incidence and Mortality of Pneumothorax in a Neonatal Intensive Care Unit in Isfahan, Iran. Chinese Journal of Contemporary Pediatrics, 12, 417-420.
[8] Apiliogullari, B., Sunam, G., Ceran, S. and Koc, H. (2011) Evaluation of Neonatal Pneumothorax. Journal of International Medical Research, 39, 2436-2440. [Google Scholar] [CrossRef] [PubMed]
[9] Mosalli, R. (2023) Clinical Profile and Outcome of Neonatal Pneumothorax: Seven Years of Experience in a Tertiary Care Center. Cureus, 15, e37625. [Google Scholar] [CrossRef] [PubMed]
[10] 杨王建, 吴杰, 樊慧苏, 林建军, 吴月瑛. 晚期早产儿和足月儿呼吸窘迫综合征并发气胸临床危险因素分析及预测模型建立[J]. 中国妇幼保健, 2023, 38(4): 691-696.
[11] 陈丹, 郭爱萍, 王院方. 新生儿气胸相关危险因素分析[J]. 医药论坛杂志, 2020, 41(6): 100-102.
[12] Duong, H.H., Mirea, L., Shah, P.S., Yang, J., Lee, S.K. and Sankaran, K. (2014) Pneumothorax in Neonates: Trends, Predictors and Outcomes. Journal of Neonatal-Perinatal Medicine, 7, 29-38. [Google Scholar] [CrossRef] [PubMed]
[13] García-Muñoz Rodrigo, F., Urquía Martí, L., Galán Henríquez, G., Rivero Rodríguez, S., Tejera Carreño, P., Molo Amorós, S., et al. (2016) Perinatal Risk Factors for Pneumothorax and Morbidity and Mortality in Very Low Birth Weight Infants. The Journal of Maternal-Fetal & Neonatal Medicine, 30, 2679-2685. [Google Scholar] [CrossRef] [PubMed]
[14] Boo, N.Y. and Ang, E.L.L. (2023) Epidemiology of Neonatal Pneumothorax Developed Spontaneously and during Respiratory Supports in Neonatal Intensive Care Units. Malaysian Journal of Pathology, 45, 441-456.
[15] 黄启坤. 新生儿气胸危险因素临床分析及胸腔闭式引流对气胸治疗的影响[J]. 中国妇幼保健, 2019, 34(24): 5655-5658.
[16] 王春艳. 新生儿气胸危险因素分析及治疗研究[J]. 临床军医杂志, 2018, 46(12): 1426-1428.
[17] 方世鹏. 新生儿气胸的诊断方式危险因素及治疗情况分析[J]. 中国妇幼保健, 2022, 37(4): 645-647.
[18] Baudat-Nguyen, J., Schneider, J., Roth-Kleiner, M., Barrielle, L., Diebold, P., Duvoisin, G., et al. (2023) Incidence and Management of Neonatal Pneumothorax in a 10-Hospital Regional Perinatal Network in Switzerland: A Retrospective Observational Study. American Journal of Perinatology, 41, e3305-e3312. [Google Scholar] [CrossRef] [PubMed]
[19] Cizmeci, M.N., Kanburoglu, M.K., Akelma, A.Z., Andan, H., Akin, K. and Tatli, M.M. (2014) An Abrupt Increment in the Respiratory Rate Is a Sign of Neonatal Pneumothorax. The Journal of Maternal-Fetal & Neonatal Medicine, 28, 583-587. [Google Scholar] [CrossRef] [PubMed]
[20] Takeno, S., Wisanuyotin, S., Jiravuttipong, A., Sirivichayakul, C. and Limkittikul, K. (2013) Risk Factors and Outcome of Atypical Acute Post-Streptococcal Glomerulonephritis in Pediatrics. The Southeast Asian Journal of Tropical Medicine and Public Health, 44, 281-288.
[21] Alrajhi, K., Woo, M.Y. and Vaillancourt, C. (2012) Test Characteristics of Ultrasonography for the Detection of Pneumothorax: A Systematic Review and Meta-Analysis. Chest, 141, 703-708. [Google Scholar] [CrossRef] [PubMed]
[22] 张爱军, 王银昌, 王超. 床旁DR摄影在新生儿气胸诊断中的应用[J]. 中华临床医师杂志(电子版), 2015, 9(22): 4258-4260.
[23] 游芳, 任雪云, 牛峰海, 赵静, 强光峰, 向美芹. 床旁肺脏超声评估肺表面活性物质治疗新生儿呼吸窘迫综合征疗效的价值[J]. 中华新生儿科杂志(中英文), 2019, 34(1): 34-37.
[24] Zong, H., Huang, Z., Zhao, J., Lin, B., Fu, Y., Lin, Y., et al. (2022) The Value of Lung Ultrasound Score in Neonatology. Frontiers in Pediatrics, 10, Article 791664. [Google Scholar] [CrossRef] [PubMed]
[25] Nobile, S., Sette, L., Esposito, C., Riitano, F., Di Sipio Morgia, C., Sbordone, A., et al. (2024) Diagnostic Accuracy of Lung Ultrasound in Neonatal Diseases: A Systematized Review. Journal of Clinical Medicine, 13, Article 3107. [Google Scholar] [CrossRef] [PubMed]
[26] 叶春秀, 郭吉锋, 蒋霞, 张静, 祁玉霞, 于婷芹. 肺脏超声检查在新生儿气胸及治疗效果的临床价值[J]. 医学影像学杂志, 2021, 31(5): 779-782.
[27] Gregory, A., Ewer, A.K. and Singh, A. (2018) Is High-Concentration Oxygen Therapy More Effective than Targeted Oxygen Therapy in Neonatal Non-Tension Pneumothorax? Archives of Disease in Childhood, 104, 405-406. [Google Scholar] [CrossRef] [PubMed]
[28] Saugstad, O. (1996) Mechanisms of Tissue Injury by Oxygen Radicals: Implications for Neonatal Disease. Acta Paediatrica, 85, 1-4. [Google Scholar] [CrossRef] [PubMed]
[29] Murphy, M.C., Heiring, C., Doglioni, N., Trevisanuto, D., Blennow, M., Bohlin, K., et al. (2018) Effect of Needle Aspiration of Pneumothorax on Subsequent Chest Drain Insertion in Newborns: A Randomized Clinical Trial. JAMA Pediatrics, 172, 664-669. [Google Scholar] [CrossRef] [PubMed]
[30] Bruschettini, M., Romantsik, O., Zappettini, S., O’Donnell, C.P. and Calevo, M.G. (2019) Needle Aspiration versus Intercostal Tube Drainage for Pneumothorax in the Newborn. Cochrane Database of Systematic Reviews, No, 1, CD011724. [Google Scholar] [CrossRef] [PubMed]
[31] 陆琴, 李红新, 屠文娟, 黄颖兰, 张琴芬. 新型胸腔引流管用于新生儿胸腔闭式引流的疗效分析[J]. 中国新生儿科杂志, 2016, 31(6): 457-459.
[32] Panza, R., Prontera, G., Ives, K.N., Zivanovic, S., Roehr, C.C., Quercia, M., et al. (2019) Pigtail Catheters versus Traditional Chest Drains for Pneumothorax Treatment in Two NICUs. European Journal of Pediatrics, 179, 73-79. [Google Scholar] [CrossRef] [PubMed]
[33] Halibullah, I., Hammond, F., Hodgson, K., Duffy, N., Stewart, M. and Sett, A. (2022) Management of Pneumothorax in Neonatal Retrieval: A Retrospective Cohort Study. Archives of Disease in Childhood—Fetal and Neonatal Edition, 108, 182-187. [Google Scholar] [CrossRef] [PubMed]
[34] Aurilia, C., Ricci, C., Tana, M., Tirone, C., Lio, A., Gambacorta, A., et al. (2017) Management of Pneumothorax in Hemodynamically Stable Preterm Infants Using High Frequency Oscillatory Ventilation: Report of Five Cases. Italian Journal of Pediatrics, 43, Article No. 114. [Google Scholar] [CrossRef] [PubMed]
[35] 陈丹, 黄西林, 李小萍. 高频振荡通气在新生儿气胸治疗中的临床观察[J]. 中国当代儿科杂志, 2012, 14(7): 499-501.

为你推荐