从“风邪伏肺”论小儿咳嗽变异性哮喘的证候演变规律——基于200例患儿的横断面调查

Discussion on the Evolution of Syndromes of Cough Variant Asthma in Children from the Perspective of “Wind Pathogen Invading the Lungs” —Based on a Cross-Sectional Survey of 200 Children

摘要: 通过对200例小儿咳嗽变异性哮喘患儿进行横断面调查，探讨基于“风邪伏肺”的证候演变规律。结果显示，患儿初期以风邪犯肺证为主(77.6%)，随病程进展，4~6个月风痰阻肺证占比达62.5%，后期肺脾气虚证、肺肾阴虚证占比逐渐升高。研究表明，该病证候演变呈现从风邪犯肺到风痰阻肺，再到肺脾肾亏虚的规律，“风邪伏肺”是重要病机。此结果可为临床辨证论治提供依据，提高治疗针对性。

Abstract: Through a cross-sectional survey of 200 children with cough variant asthma, the syndrome evolution pattern based on “wind pathogen invading the lungs” was explored. The results showed that in the early stage of the disease, the syndrome of wind pathogen invading the lung was predominant (77.6%). As the disease progressed, the proportion of wind-phlegm obstructing the lung reached 62.5% within 4 to 6 months. In the later stage, the proportions of lung-spleen qi deficiency syndrome and lung-kidney Yin deficiency syndrome gradually increased. Research shows that the evolution of the syndrome of this disease follows a pattern from wind pathogen invading the lungs to wind-phlegm blocking the lungs, and then to deficiency of the lungs, spleen and kidneys. “Wind pathogen subduing the lungs” is an important pathogenesis. This result can provide a basis for clinical syndrome differentiation and treatment, and improve the pertinence of treatment.