进展期胆囊癌行腹腔镜胆囊癌根治术的意义与展望
The Significance and Prospect of Laparoscopic Radical Cholecystectomy for Advanced Gallbladder Cancer
摘要: 胆囊癌是一种预后极差的恶性肿瘤，对于具备手术指征的胆囊癌患者，根治性切除仍是目前唯一被证实可延长生存期的治愈性治疗；肿瘤分期决定手术范围——Tis/T1a期病变通过单纯胆囊切除即可达根治，对于T1b及以上的进展期胆囊癌，胆囊癌根治术是首选方式；进展期胆囊癌(GBC)传统依赖开放根治术，近年来，得益于腹腔镜设备与术式的革新，针对胆囊癌的腹腔镜根治性胆囊切除术(laparoscopic radical cholecystectomy, LRC)在胆囊癌外科治疗中再度成为焦点。本文将探讨进展期胆囊癌行腹腔镜下胆囊癌根治术的现状、优势与挑战，并展望其未来发展方向。
Abstract: Gallbladder carcinoma (GBC) represents a malignant neoplasm with an exceptionally poor prognosis. For patients presenting with operable indications, radical resection remains the sole curative treatment modality with proven efficacy in prolonging survival. The extent of surgical intervention is determined by tumor staging: Tis/T1a lesions can be adequately managed through simple cholecystectomy, while radical cholecystectomy constitutes the primary approach for T1b and more advanced stages. Historically, advanced GBC has been predominantly treated via open radical surgery; however, recent advancements in laparoscopic instrumentation and surgical techniques have rekindled interest in laparoscopic radical cholecystectomy (LRC) as a focal point in the surgical management of gallbladder carcinoma. This article will comprehensively examine the current status, advantages, and challenges associated with laparoscopic radical cholecystectomy for advanced gallbladder carcinoma, while also providing insights into its future developmental trajectory.
文章引用：杨欣怡, 邹仁超, 魏东. 进展期胆囊癌行腹腔镜胆囊癌根治术的意义与展望[J]. 临床医学进展, 2025, 15(9): 70-77. https://doi.org/10.12677/acm.2025.1592458

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