急性缺血性卒中预后的炎症生物标志物研究进展
Research Advances in Inflammatory Biomarkers for the Prognosis of Acute Ischemic Stroke
DOI: 10.12677/acm.2025.1592477, PDF,   
作者: 张凯睿, 李美琪, 张佳慧, 魏小彤：延安大学咸阳医院神经内科，陕西 咸阳；延安大学医学院，陕西 延安；郭爱红*, 张 能：延安大学咸阳医院神经内科，陕西 咸阳
关键词: 缺血性卒中；炎症；预后；Ischemic Stroke； Inflammation； Prognosis
摘要: 本文综述了炎症相关生物标志物与急性缺血性脑卒中(AIS)预后的关系。AIS起病急、危害大，87%的卒中为缺血性，我国患者超千万且致残率高。急性缺血性卒中(AIS)预后异质性强，炎症反应是继发性神经损伤的关键机制，相关标志物与预后是否良好有极大的相关性。高敏C反应蛋白(hsCRP)、白细胞介素家族、血细胞标志物等都展示出了巨大的潜力。本文就血液中常见的、易获得的炎性指标在急性缺血性卒中患者预后预测中的临床应用进行综述。
Abstract: This review summarizes the relationship between inflammation-related biomarkers and the prognosis of acute ischemic stroke (AIS). AIS is characterized by sudden onset and severe consequences, constituting 87% of all stroke cases. In China, the AIS patient population exceeds ten million and carries a high disability rate. Prognosis following AIS exhibits significant heterogeneity. The inflammatory response is a key mechanism underlying secondary neuronal injury, and related biomarkers show substantial correlation with favorable versus unfavorable outcomes. High-sensitivity C-reactive protein (hsCRP), the interleukin family, hematological markers, and others have demonstrated considerable potential. This article reviews the clinical utility of common, readily accessible inflammatory indicators in blood for predicting the prognosis of patients with acute ischemic stroke.
文章引用：张凯睿, 郭爱红, 张能, 李美琪, 张佳慧, 魏小彤. 急性缺血性卒中预后的炎症生物标志物研究进展[J]. 临床医学进展, 2025, 15(9): 215-222. https://doi.org/10.12677/acm.2025.1592477

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