保留比值受损肺功能人群的临床研究进展
Clinical Research Progress in Individuals with Preserved Ratio Impaired Spirometry
DOI: 10.12677/acm.2025.1592495, PDF,   
作者: 钟 田*：延安大学医学院，陕西 延安；张彩莲#：延安大学附属医院呼吸内科，陕西 延安
关键词: 保留比值受损肺功能；慢性阻塞性肺疾病；肺功能检查；Preserved Ratio Impaired Spirometry； Chronic Obstructive Pulmonary Disease； Pulmonary Function Test
摘要: 保留比值受损肺功能(PRISm)作为一种重要的慢性阻塞性肺疾病(COPD)前期表型，近年引起学界高度关注。该人群虽未达COPD肺功能诊断标准(FEV1/FVC ≥ 0.7)，但存在肺功能指标(FEV1和/或FVC < 80%预计值)损害、影像学异常，且不良预后风险显著增高。本文系统梳理近期PRISm相关文献，聚焦其流行病学特征、风险因素、临床分型、临床特征、检查手段，旨在为PRISm人群的早期识别、干预策略制定及未来研究方向提供依据。
Abstract: Preserved ratio impaired spirometry (PRISm), recognized as a significant pre-COPD phenotype, has attracted considerable research interest. Individuals with PRISm do not fulfill diagnostic criteria for COPD yet demonstrate impaired lung function, frequent radiological abnormalities, and elevated risks of adverse outcomes. This review synthesizes current evidence on PRISm, encompassing its epidemiology, risk determinants, clinical typing, clinical characteristics, diagnostic approaches, with the goal of informing early detection, intervention, and clinical investigation for this population.
文章引用：钟田, 张彩莲. 保留比值受损肺功能人群的临床研究进展[J]. 临床医学进展, 2025, 15(9): 340-346. https://doi.org/10.12677/acm.2025.1592495

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