化学剥脱术联合其他治疗策略在治疗痤疮中的研究进展

Research Progress of Chemical Peeling Combined with Other Treatment Strategies in the Treatment of Acne

摘要: 痤疮是一种常见的、复杂的、多因素的炎症性皮肤病，可引发色素沉着和瘢痕，严重影响患者的身心健康。既往痤疮的治疗以药物治疗为主，虽短期改善症状，但长期用药易产生耐药性和药物不良反应，限制患者不能长期用药，导致病情反复。近年来，化学剥脱术因其可以有效改善痤疮病变、起效快、无需全身用药的优势被广泛应用于痤疮的治疗中，但其效果有限、需多次治疗且易出现不良反应常常影响治疗效果。因此，痤疮的治疗中常将化学剥脱术与其他治疗策略联合进行，以提升治疗效果的安全性和有效性。本文对化学剥脱术联合策略的应用进展进行综述，旨在为痤疮的临床治疗提供更多选择。

Abstract: Acne is a common, complex and multi-factorial inflammatory skin disease, which can cause pigmentation and scarring, seriously affecting the physical and mental health of patients. The treatment of acne in the past is mainly based on drug treatment. Although the symptoms are improved in the short term, the long-term use of drugs is prone to drug resistance and adverse drug reactions, which limits the patient’s inability to use drugs for a long time, resulting in repeated illness. In recent years, chemical peeling has been widely used in the treatment of acne because of its advantages of effectively improving acne lesions, rapid onset and no need for systemic medication. However, its effect is limited, requires multiple treatments and prone to adverse reactions, which often affect the therapeutic effect. Therefore, in the treatment of acne, chemical peeling is often combined with other treatment strategies to improve the safety and effectiveness of the treatment effect. This article reviews the application progress of the combined strategy of chemical peeling, aiming to provide more options for the clinical treatment of acne.