胆管内乳头状粘液性肿瘤一例报道
Intraductal Papillary Mucinous Neoplasm of the Bile Duct: A Case Report
DOI: 10.12677/acm.2025.1592518, PDF,   
作者: 王建勇：赣南医科大学第一临床医学院，江西 赣州；何 晓*：赣南医科大学第一附属医院肝胆胰外科，江西 赣州
关键词: 胆管肿瘤；胆管内乳头状粘液性肿瘤；诊断；手术；治疗；Bile Duct Tumor； Intraductal Papillary Mucinous Neoplasm of the Bile Duct； Diagnosis； Surgery； Treatment
摘要: 报道1例51岁女性患者，因“外院体检彩超检查发现肝内占位性病变1天”就诊于赣南医科大学第一附属医院，经右半肝切除术，术后病理证实为：胆管内乳头状粘液性肿瘤，随访1年，未发生复发及转移。
Abstract: We report the case of a 51-year-old woman who was referred to The First Affiliated Hospital of Gannan Medical University after an abdominal ultrasound during a routine health examination at an external facility revealed a hepatic mass. The patient underwent a right hemihepatectomy, and postoperative pathology confirmed the diagnosis of intraductal papillary mucinous neoplasm (IPMN) of the bile duct. At the one-year follow-up, there was no evidence of recurrence or metastasis.
文章引用：王建勇, 何晓. 胆管内乳头状粘液性肿瘤一例报道[J]. 临床医学进展, 2025, 15(9): 496-503. https://doi.org/10.12677/acm.2025.1592518

参考文献

[1] Kim, J.R., Jang, K. and Jang, J. (2023) Intraductal Papillary Neoplasm of the Bile Duct: Review of Updated Clinicopathological and Imaging Characteristics. British Journal of Surgery, 110, 1229-1240. [Google Scholar] [CrossRef] [PubMed]
[2] Bosman, F.T., Carneiro, F., Hruban, R.H., et al. (2010) WHO Classification of Tumours of the Digestive System. IARC Publications.
[3] Zen, Y. and Akita, M. (2023) Neoplastic Progression in Intraductal Papillary Neoplasm of the Bile Duct. Archives of Pathology & Laboratory Medicine, 148, 989-996. [Google Scholar] [CrossRef] [PubMed]
[4] Noguchi, D., Kuriyama, N., Kozuka, Y., Komatubara, H., Sakamoto, T., Ito, T., et al. (2025) A Recent Update on the Morphological Classification of Intraductal Papillary Neoplasm of the Bile Duct: Correlation with Postoperative Prognosis and Pathological Features. PLOS One, 20, e0325081. [Google Scholar] [CrossRef] [PubMed]
[5] Nakanuma, Y., Kakuda, Y., Sugino, T., Sato, Y. and Fukumura, Y. (2022) Pathologies of Precursor Lesions of Biliary Tract Carcinoma. Cancers, 14, Article 5358. [Google Scholar] [CrossRef] [PubMed]
[6] Nakanuma, Y., Kakuda, Y., Canh, H.N., Sasaki, M., Harada, K. and Sugino, T. (2024) Pathologic Characterization of Precursors and Cholangiocarcinoma Referring to Peribiliary Capillary Plexus: A New Pathologic Approach to Bile Duct Neoplasm. Virchows Archiv, 485, 257-268. [Google Scholar] [CrossRef] [PubMed]
[7] Nakanuma, Y., Li, Z., Sato, Y., Sasaki, M., Harada, K., Kakuda, Y., et al. (2024) A Pathological Assessment of the Microvasculature of Biliary Tract Neoplasms Referring to Pre-Existing Blood Vessels and Vessel Co-Option. Cancers, 16, Article 3869. [Google Scholar] [CrossRef] [PubMed]
[8] Fu, C., Jin, H., Wang, Y. and Xu, H. (2024) Clinicopathological Features and Surgical Treatments of Intraductal Papillary Neoplasm of the Bile Duct: A Case Report and Literature Review. Frontiers in Medicine, 11, Article 1443599. [Google Scholar] [CrossRef] [PubMed]
[9] Liu, L., Xu, H., Zheng, S., Sun, L., Guo, L., Zhang, Y., et al. (2014) Ultrasound Findings of Intraductal Papillary Neoplasm in Bile Duct and the Added Value of Contrast-Enhanced Ultrasound. Ultraschall in der Medizin—European Journal of Ultrasound, 36, 594-602. [Google Scholar] [CrossRef] [PubMed]
[10] Möller, K., Braden, B., Jenssen, C., Ignee, A., Cui, X.W., Yamashita, Y., et al. (2023) Intraductal Papillary Neoplasms of the Bile Ducts—What Can Be Seen with Ultrasound? Endoscopic Ultrasound, 12, 445-455. [Google Scholar] [CrossRef] [PubMed]
[11] Li, J., Yu, Y., Zhu, L., Li, Y. and He, Q. (2020) Magnetic Resonance Imaging versus Computed Tomography for Biliary Tract Intraductal Papillary Mucinous Neoplasm (BT-IPMN): A Diagnostic Performance Analysis. Medical Science Monitor, 26, e920952-1. [Google Scholar] [CrossRef] [PubMed]
[12] Youn, J.M., Hwang, S., Ahn, C., Moon, D., Ha, T., Song, G., et al. (2022) Clinicopathological Features and Long-Term Outcomes of Intraductal Papillary Neoplasms of the Bile Duct of the Liver: Single-Institution Experience with 146 Patients. Journal of Gastrointestinal Surgery, 26, 1394-1405. [Google Scholar] [CrossRef] [PubMed]
[13] Lee, S., Kim, M., Kim, S., Choi, D., Jang, K. and Park, Y.N. (2019) Intraductal Papillary Neoplasm of the Bile Duct: Assessment of Invasive Carcinoma and Long-Term Outcomes Using MRI. Journal of Hepatology, 70, 692-699. [Google Scholar] [CrossRef] [PubMed]
[14] Tringali, A., Milluzzo, S.M., Ardito, F., Laurenzi, A., Ettorre, G.M., Barbaro, B., et al. (2022) Peroral-Cholangioscopy to Plan Surgery for Protruding Biliary Lesions: Report of Four Cases. Therapeutic Advances in Gastrointestinal Endoscopy, 15. [Google Scholar] [CrossRef] [PubMed]
[15] Gordon-Weeks, A.N., Jones, K., Harriss, E., Smith, A. and Silva, M. (2016) Systematic Review and Meta-Analysis of Current Experience in Treating IPNB: Clinical and Pathological Correlates. Annals of Surgery, 263, 656-663. [Google Scholar] [CrossRef] [PubMed]
[16] Wang, X. (2015) Biliary Tract Intraductal Papillary Mucinous Neoplasm: Report of 19 Cases. World Journal of Gastroenterology, 21, 4261-4267. [Google Scholar] [CrossRef] [PubMed]
[17] Kim, J.R., Lee, K., Kwon, W., Kim, E., Kim, S. and Jang, J. (2018) Comparison of the Clinicopathologic Characteristics of Intraductal Papillary Neoplasm of the Bile Duct According to Morphological and Anatomical Classifications. Journal of Korean Medical Science, 33, e266. [Google Scholar] [CrossRef] [PubMed]
[18] Luvira, V., Pugkhem, A., Bhudhisawasdi, V., Pairojkul, C., Sathitkarnmanee, E., Luvira, V., et al. (2017) Long‐Term Outcome of Surgical Resection for Intraductal Papillary Neoplasm of the Bile Duct. Journal of Gastroenterology and Hepatology, 32, 527-533. [Google Scholar] [CrossRef] [PubMed]
[19] Mocchegiani, F., Vincenzi, P., Conte, G., Nicolini, D., Rossi, R., Cacciaguerra, A.B., et al. (2023) Intraductal Papillary Neoplasm of the Bile Duct: The New Frontier of Biliary Pathology. World Journal of Gastroenterology, 29, 5361-5373. [Google Scholar] [CrossRef] [PubMed]
[20] Inoue, M., Shimoda, E., Rikihisa, S. and Isohashi, F. (2025) A Case of Stereotactic Body Radiotherapy for Inoperable Intraductal Papillary Neoplasm of the Bile Duct. Cureus, 17, e80916. [Google Scholar] [CrossRef] [PubMed]
[21] Nakahata, A., Yamashita, Y., Yamazaki, H., Tsuda, I., Kawaji, Y., Ashida, R., et al. (2024) Intraductal Papillary Neoplasm of the Bile Duct Treated with Argon Plasma Coagulation via Endoscopic Ultrasound-Guided Choledochoduodenostomy. Internal Medicine, 63, 957-962. [Google Scholar] [CrossRef] [PubMed]
[22] Wu, Y., Gu, W., Cheung, K.S., Yang, J., Zhang, X. and Jin, H. (2024) Cholangioscopy-Guided Laser Ablation for Intraductal Papillary Neoplasm of Bile Duct. Endoscopy, 56, E636-E637. [Google Scholar] [CrossRef] [PubMed]
[23] Zhang, Y., Liang, Y., Liu, Y. and Feng, Y. (2022) Photodynamic Therapy for Hepatic Hilar Intraductal Papillary Neoplasm of the Bile Duct: A Case Report. VideoGIE, 7, 178-181. [Google Scholar] [CrossRef] [PubMed]

为你推荐