细胞自噬在CRC转移中的作用及研究进展
The Role and Research Progress of Autophagy in Colorectal Cancer Metastasis
DOI: 10.12677/hjbm.2025.155100, PDF,    科研立项经费支持
作者: 许洁斌:嘉兴大学医学院,浙江 嘉兴
关键词: 自噬结直肠癌转移Autophagy CRC (Colorectal Cancer) Metastasis
摘要: 细胞自噬(autophagy),作为真核生物中高度保守的生物学过程,在结直肠癌(colorectal cancer, CRC)转移过程中具有双重作用。晚期CRC预后较差,易发生转移,且转移过程中通常伴有细胞自噬发生。多种细胞因子通过调控细胞自噬,促进或抑制CRC转移。在本文中我们探讨不同细胞因子如何通过调控细胞自噬影响CRC转移。
Abstract: Autophagy, as a highly conserved biological process in eukaryotes, plays a dual role in the metastasis of colorectal cancer (CRC). The prognosis of advanced CRC is poor, and it is prone to metastasis. During the metastasis process, autophagy usually occurs. Various cytokines regulate autophagy and either promote or inhibit the metastasis of CRC. In this article, we explore how different cytokines affect CRC metastasis by regulating autophagy.
文章引用:许洁斌. 细胞自噬在CRC转移中的作用及研究进展[J]. 生物医学, 2025, 15(5): 947-953. https://doi.org/10.12677/hjbm.2025.155100

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