恶性肿瘤合并脓毒血症生物标志物的研究进展
Research Progress on Biomarkers for Malignant Tumor Patients Complicated with Sepsis
DOI: 10.12677/acm.2025.1592533, PDF,    科研立项经费支持
作者: 方章兰*, 杨湖广, 祝筱茜, 罗 玲#：重庆大学附属肿瘤医院普通内科，重庆
关键词: 恶性肿瘤；脓毒血症；生物标志物；早期诊断；预后；Malignant Tumor； Sepsis； Biomarkers； Early Diagnosis； Prognosis
摘要: 恶性肿瘤患者免疫功能显著低下，且在抗肿瘤治疗过程中免疫屏障进一步受损，极易并发脓毒血症。一旦合并脓毒血症，患者病情往往进展迅速，死亡率显著升高。因此，早期准确诊断对改善预后至关重要，而相关标志物的精准检测在这一过程中发挥关键作用。本文系统综述了近年来恶性肿瘤合并脓毒血症相关标志物的研究进展，旨在为早期识别、精准诊断及有效治疗提供参考依据。
Abstract: Malignant tumor patients exhibit significantly compromised immune function, and their immune barriers are further damaged during anti-tumor therapy, making them highly susceptible to sepsis. Once sepsis occurs, the condition often progresses rapidly, leading to a markedly increased mortality rate. Therefore, early and accurate diagnosis is crucial for improving prognosis, and the precise detection of relevant biomarkers plays a key role in this process. This article systematically reviews recent research advances in biomarkers for sepsis in malignant tumor patients, aiming to provide a reference for early identification, precise diagnosis, and effective treatment.
文章引用：方章兰, 杨湖广, 祝筱茜, 罗玲. 恶性肿瘤合并脓毒血症生物标志物的研究进展[J]. 临床医学进展, 2025, 15(9): 606-612. https://doi.org/10.12677/acm.2025.1592533

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