肺保护性通气策略与PEEP滴定的研究进展
Research Progress on Lung Protective Ventilation Strategy and PEEP Titration
DOI: 10.12677/acm.2025.1592581, PDF,   
作者: 王楚嫣, 田津瑜, 苗娜娜, 向思琳：延安大学医学院，陕西 延安；延安大学附属医院麻醉与围术期医学科，陕西 延安；郑 军*：延安大学附属医院麻醉与围术期医学科，陕西 延安
关键词: 肺保护性通气；PEEP滴定；驱动压；个体化通气；急性呼吸窘迫综合征；Pulmonary Protective Ventilation； PEEP Titration； Drive Pressure； Individualized Ventilation； Acute Respiratory Distress Syndrome
摘要: 肺保护性通气策略(LPVS)和呼气末正压(PEEP)滴定是急性呼吸窘迫综合征(ARDS)及围手术期呼吸管理的关键组成部分。本文系统综述了近年来相关研究进展，聚焦PEEP滴定方法、驱动压导向通气、个体化通气策略及其在不同临床情境中的应用效果。研究表明，尽管肺保护性通气原则已获广泛认可，但最佳PEEP滴定策略仍存争议，个体化选择与实施面临挑战。未来研究需进一步探索精准化PEEP滴定方法、多模态监测技术整合及特殊人群的优化策略，以改善患者预后并减少呼吸机相关肺损伤。
Abstract: Pulmonary protective ventilation strategy (LPVS) and positive end expiratory pressure (PEEP) titration are key components of acute respiratory distress syndrome (ARDS) and perioperative respiratory management. This article provides a systematic review of recent research progress, focusing on PEEP titration methods, pressure guided ventilation, individualized ventilation strategies, and their application effects in different clinical contexts. Research has shown that although the principle of lung protective ventilation has been widely recognized, the optimal PEEP titration strategy is still controversial, and individualized selection and implementation face challenges. Future research needs to further explore precise PEEP titration methods, integration of multimodal monitoring technologies, and optimization strategies for special populations to improve patient prognosis and reduce ventilator-associated lung injury.
文章引用：王楚嫣, 田津瑜, 苗娜娜, 向思琳, 郑军. 肺保护性通气策略与PEEP滴定的研究进展[J]. 临床医学进展, 2025, 15(9): 969-974. https://doi.org/10.12677/acm.2025.1592581

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