原发性膜性肾病预后生物标志物的研究进展
Research Advances in Prognostic Biomarkers of Primary Membranous Nephropathy
DOI: 10.12677/acm.2025.1592597, PDF,   
作者: 李易真：赣南医科大学第一临床医学院，江西 赣州；汤显湖*, 王润秀：赣南医科大学第一附属医院肾内科，江西 赣州
关键词: 原发性膜性肾病；预后；标志物；Membranous Nephropathy； Prognosis； Biomarkers
摘要: 膜性肾病(Membranous Nephropathy, MN)是成人肾病综合征(Nephrotic Syndrome, NS)的主要病因，预后因个体化具有差异性。部分患者可能在10年内发展至终末期肾病(End-stage renal disease, ESRD)。因此迫切需要无创且可靠的生物标志物来早期识别中高危患者，延缓疾病进展和改善预后。本文将对原发性膜性肾病(Primary membranous nephropathy, PMN)的预后生物标志物进行叙述，旨在为膜性肾病的病情评估、早期干预及预后改善提供参考。
Abstract: Membranous Nephropathy (MN) is a leading cause of Nephrotic Syndrome (NS) in adults, and its prognosis varies considerably among individuals. Some patients may progress to end-stage renal disease (ESRD) within 10 years. Therefore, there is an urgent need for non-invasive and reliable biomarkers to early identify patients at intermediate to high risk, in order to delay disease progression and improve outcomes. This article reviews prognostic biomarkers for primary membranous nephropathy (PMN), aiming to provide references for disease assessment, early intervention, and prognosis improvement in MN.
文章引用：李易真, 汤显湖, 王润秀. 原发性膜性肾病预后生物标志物的研究进展[J]. 临床医学进展, 2025, 15(9): 1095-1101. https://doi.org/10.12677/acm.2025.1592597

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